Publications by authors named "Vladimir Anfertev"

Article Synopsis
  • - The use of metabolomics in diagnostics and therapy monitoring is gaining traction in modern medicine, offering a new approach to understanding diseases.
  • - Terahertz nonstationary spectroscopy is a sensitive technique that can analyze gas mixtures and identify metabolites from the thermal decomposition of biological samples.
  • - The study reported groundbreaking results by applying high-resolution terahertz spectroscopy to pathological samples, leading to the identification of similar metabolites in cystic tissues across different organ systems.
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A THz nonstationary high-resolution spectrometer based on semiconductor superlattice multipliers is applied to investigate the dynamics of urine composition for cancer patients treated with chemotherapy. The molecular urine composition of healthy volunteers and cancer patients was compared and contrasted. We have found a set of nitriles that either appeared after chemotherapy or increased in content, which are expected as a result of bio-chemical damage to the liver.

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Significance: One of the modern trends in medical diagnostics is based on metabolomics, an approach allowing determination of metabolites which can be the specific features of disease. High-resolution gas spectroscopy allows investigation of the gas metabolite content of samples of biological origin. We present the elaboration of a method of studying diabetic and non-diabetic biological samples, prepared as pellets, by terahertz (THz) high-resolution spectroscopy.

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Significance: The creation of fundamentally new approaches to storing various biomaterial and estimation parameters, without irreversible loss of any biomaterial, is a pressing challenge in clinical practice. We present a technology for studying samples of diabetic and non-diabetic human blood plasma in the terahertz (THz) frequency range.

Aim: The main idea of our study is to propose a method for diagnosis and storing the samples of diabetic and non-diabetic human blood plasma and to study these samples in the THz frequency range.

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