Publications by authors named "Vlad Gorduza"
Article Synopsis
- Fetal nucleated red blood cells (NRBC) can be found in maternal blood and are useful for fetal genetic evaluation, prompting a study that compared two methods for isolating these cells.
- The study involved processing blood samples from 27 pregnant women, using either hemoglobin-based enrichment or anti-CD71 magnetic selection to isolate NRBCs, followed by identifying them with fluorescence in situ hybridization (FISH).
- Results showed that hemoglobin-based enrichment was significantly more effective at isolating NRBCs and confirming fetal cells compared to the anti-CD71 method, making it a simpler and more efficient approach.
The use of nuchal translucency (NT) in 1992 by Nicolaides et al was a major breakthrough in screening for chromosomal aneuploidies at the end of the first trimester. However, pathological conditions other than chromosomal aneuploidies are also associated with increased NT, which can also be detected in normal fetuses. This study sought to evaluate the causes of this ultrasound sign in a group of patients from Iasi, Romania.
View Article and Find Full Text PDFA rare cause of infertility is the lack of fertilisation with the spontaneous activation of oocytes, leading to parthenogenesis. We present such a case. The patient was a G1P0 38-year-old woman of African ethnicity, who requested an in vitro fertilisation (IVF) with donor sperm.
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