Publications by authors named "Vlad Dzavik"
Article Synopsis
- - Electro-mechanical noise caused by multiple coronary wires can interfere with pacing in patients who rely on pacemakers, potentially leading to a dangerously slow heart rate (asystole).
- - Recognizing this issue is crucial for effective treatment strategies to ensure patient safety.
- - Management options include adjusting device sensitivity, switching to asynchronous pacing, removing the problematic wire, or using a temporary pacing system.
Article Synopsis
- Chronic kidney disease (CKD) increases the risk of complications after percutaneous coronary intervention (PCI), and it's unclear how genetic factors like CYP2C19 loss of function (LOF) alleles affect this risk or the safety of genotype-guided therapy.
- A study with 5,815 patients analyzed outcomes based on CKD status and found no significant interaction between treatment strategy and CKD for major cardiovascular events or bleeding risks after 12 months.
- The findings suggest that while escalating P2Y inhibitor therapy via a genotype-guided approach doesn't reduce complications in CKD patients, it also doesn't increase bleeding risks, indicating the need for larger studies to confirm these results.
Background: Mortality from COVID-19 is high among hospitalized patients and effective therapeutics are lacking. Hypercoagulability, thrombosis and hyperinflammation occur in COVID-19 and may contribute to severe complications. Therapeutic anticoagulation may improve clinical outcomes through anti-thrombotic, anti-inflammatory and anti-viral mechanisms.
View Article and Find Full Text PDFBackground: The objective of this study was to assess the efficacy of sealing intermediate nonobstructive coronary saphenous vein graft (SVG) lesions with drug-eluting stents (DES; paclitaxel- or everolimus-eluting stents) for reducing major adverse cardiac events (MACE).
Methods And Results: This was a randomized controlled multicenter clinical trial that enrolled patients with a previous coronary artery bypass graft who had developed at least 1 intermediate nonobstructive SVG lesion (30%-60% diameter stenosis by visual estimation). Patients were randomized (1:1) to DES implantation (SVG-DES) or medical treatment (SVG-MT) of the target SVG lesion.
Background: Transradial percutaneous coronary intervention (PCI) results in fewer vascular complications, earlier ambulation, and improved patient comfort. Limited data exist for radial access in acute myocardial infarction, where reperfusion must occur quickly.
Methods: In a multicenter pilot trial, 50 patients with myocardial infarction requiring either primary or rescue PCI were randomized to radial or femoral access.
Objectives: We examined the clinical, angiographic, and procedural characteristics determining survival after percutaneous coronary intervention (PCI) for cardiogenic shock.
Background: The SHOCK (SHould we emergently revascularize Occluded coronaries for Cardiogenic shocK?) trial prospectively enrolled patients with shock complicating acute myocardial infarction (MI). Patients were randomized to a strategy of early revascularization or initial medical stabilization.