Publications by authors named "Vlad Braicu"
Colorectal cancer (CRC) has exhibited an increasing incidence worldwide in recent years, underscoring the importance of early diagnosis methods. This study aimed to assess the influence of CD44 gene polymorphism rs187115 on CRC susceptibility. Material and The study encompassed 470 CRC patients and 165 healthy controls.
View Article and Find Full Text PDFSentinel lymph node biopsy (SLNB) has become a method more and more frequently used in loco-regional breast cancer in the initial stages. Starting from the first report on the technical feasibility of the sentinel node method in breast cancer, published by Krag (1993) and Giuliano (1994), the method underwent numerous improvements and was also largely used worldwide. This article is a prospective study that took place at the "SJUPBT Surgery Clinic Timisoara" over a period of 1 year between July 2023 and July 2024, during which 137 underwent sentinel lymph node biopsy (SLNB) based on the current guidelines.
View Article and Find Full Text PDFColorectal cancer (CRC) has exhibited an increasing incidence worldwide in recent years, underscoring the importance of early diagnosis methods. This study aimed to assess the influence of CD44 gene polymorphism rs187115 on CRC susceptibility. Material and The study encompassed 470 CRC patients and 165 healthy controls.
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- The study investigates how preoperative inflammatory markers (like NLR, PLR, APRI, and SII) and liver function tests can predict the risk of developing fistulas after colorectal cancer surgery.
- Conducted at the "Pius Brinzeu" Clinical Emergency Hospital with data from 219 patients, the findings highlight that the Systemic Inflammation Index (SII) and albumin levels are particularly effective in predicting fistula risk.
- The research emphasizes that using these biomarkers for preoperative assessments can help doctors stratify risks and improve surgical outcomes for colorectal cancer patients.
Article Synopsis
- Pancreaticolithiasis is a rare condition often associated with chronic pancreatitis, typically resulting from prolonged inflammation and calcium buildup in the pancreatic ducts.
- A case study detailed a patient with pancreaticolithiasis due to alcoholic chronic pancreatitis, who underwent surgery with a specific technique to remove the stones and preserve splenic vessels.
- The study found that treatment for pancreaticolithiasis varies based on stone size, recommending surgical intervention for stones larger than 0.5 cm and endoscopic methods for smaller stones.
This systematic review critically evaluates the impact of systemic treatments on outcomes and quality of life (QoL) in patients with RAS-positive stage IV colorectal cancer, with studies published up to December 2023 across PubMed, Scopus, and Web of Science. From an initial pool of 1345 articles, 11 relevant studies were selected for inclusion, encompassing a diverse range of systemic treatments, including panitumumab combined with FOLFOX4 and FOLFIRI, irinotecan paired with panitumumab, regorafenib followed by cetuximab ± irinotecan and vice versa, and panitumumab as a maintenance therapy post-induction. Patient demographics predominantly included middle-aged to elderly individuals, with a slight male predominance.
View Article and Find Full Text PDFThe global pandemic period from 2020 to 2022 caused important alterations in oncology care. This study aimed to describe the trends and variations in patient characteristics, comorbidities, and treatment approaches during this time in Romania. We conducted a retrospective database search to identify patients with rectal cancer who underwent surgical intervention between 2020 and 2022 and the year 2019, which served as a pre-pandemic period control.
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