Publications by authors named "Vk Jain"

Objective/aim: To determine the incidence of steroid induced glaucoma and treatment characteristics in kidney transplant patients in a tertiary level multispecialty institution.

Methods: In this prospective cross-sectional study, the patients who underwent kidney transplant were enrolled and underwent comprehensive ophthalmological evaluation including intraocular pressure (IOP) measurement with Goldmann Applanation tonometry, visual field examination with Humphrey Field Analyzer, and gonioscopy. Cases with IOP > 21 mm Hg, visual field defect, and optic disc cupping > 0.

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Introduction: Sarcomas are a large group of malignant mesenchymal tumors. Despite being rare diseases, the disease burden of these malignant tumors on the existing healthcare infrastructure is substantial. Although previous bibliometric studies have analyzed the trends of publications on osteosarcoma and Ewing's sarcoma, no such major analyses encompassing all primary bone sarcomas have been reported hitherto.

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Background And Aims: Anterior cruciate ligament (ACL) injuries significantly impact young athletes, leading to long-term physical, psychological, and socioeconomic consequences. There is an urgent need to develop effective preventive strategies. This scoping review aims to evaluate modifiable and non-modifiable risk factors for ACL injuries and assess existing preventive strategies.

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There is an evolving role of medical journal editors in the 21st century, highlighting the challenges they face in ensuring the quality, accuracy, and relevance of published research. As gatekeepers of medical information, editors are inundated with a high volume of submissions, necessitating efficient triage and a keen understanding of diverse scientific fields. The peer review process presents its hurdles, particularly in securing timely assessments from busy experts, while ethical considerations around bias and misconduct demand rigorous scrutiny.

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Introduction: Calcific tendonitis is characterized by calcium hydroxyapatite crystal deposition in tendons, leading to inflammation and pain. While predominantly observed in the rotator cuff tendons of the shoulder, its occurrence in the rectus femoris tendon of the hip is exceedingly rare and poses a diagnostic challenge.

Case Report: A 38-year-old female housewife presented with a 1-month history of left hip pain, which was dull, aching, and exacerbated by movements such as standing and walking.

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Introduction: Enchondroma protuberans (EP), a rare form of enchondroma with exophytic growth, differs radiographically from classical enchondromas and can mimic osteochondroma, periosteal chondroma, or chondrosarcoma. Proper differentiation is crucial to avoid unnecessary radical resection, as EP requires intralesional curettage rather than the surgical removal typical for osteochondromas.

Case Report: A 14-year-old male presented with a progressively enlarging, painless mass on the lateral aspect of his left hand, initially noticed 4 years ago.

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Gold-induced cytokine (GOLDIC) is a novel orthobiologic approach utilizing gold particles to produce a serum rich in immunoregulating cytokines and growth factors, which is being explored for its potential in tissue regeneration and treating musculoskeletal issues like knee osteoarthritis (OA). This study aims to review its mechanism of action along with the outcomes of , preclinical, and clinical studies, with a secondary focus on documenting clinical trials related to its use in OA of the knee. A systematic search was conducted in four databases (Embase, Scopus, PubMed, Web of Science) for studies on GOLDIC therapy for knee OA, using specific keywords related to knee anatomy and OA.

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The emergence of antimicrobial resistance (AMR) has profoundly impacted the management of osteoarticular infections (OAIs), presenting significant challenges for healthcare systems worldwide. This review provides a comprehensive overview of the current landscape of AMR in OAIs, emphasizing the necessity for assertive and innovative strategies to combat this escalating health threat. It discusses the evolution of resistance among key pathogens, including ESKAPEE organisms, and the implications for treatment protocols and healthcare outcomes.

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Article Synopsis
  • * The review details the unique properties of these nanomaterials, such as high conductivity and increased surface area, which help enhance signal transmission and overall biosensor functionality across applications in healthcare and disease detection.
  • * It also addresses challenges like biocompatibility and stability, suggesting solutions such as advanced material engineering, and envisions a future where nanomaterial-based biosensors integrate with microfluidics and AI for better healthcare accessibility.
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Background: A major catastrophic adverse event after total joint arthroplasty surgery (TJA) is the periprosthetic joint infection (PJI). In the recent years, regional antibiotic prophylaxis has gained momentum as a novel infection control strategy in total knee arthroplasty (TKA), with different purported benefits over systemic administration. The current article was planned to comprehensively review the available evidence in literature; as well as compare the safety and effectiveness of intraosseous (IO) antibiotic prophylaxis with systemic prophylaxis in patients undergoing TJA.

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Temporomandibular joint disorder is a common condition characterized by jaw joint and muscle pain and its treatment is often multifaceted. While conventional treatment modalities exist for the same, interest has grown in exploring alternative therapies such as antioxidants for their potential analgesic properties. The prospective therapeutic use of lycopene, a naturally occurring antioxidant present in tomatoes and other fruits, as an anti-inflammatory therapeutic modality in the management of temporomandibular joint problems is examined in this narrative review.

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Article Synopsis
  • Osteoarticular tuberculosis (TB) affects the bones and joints and is a rare type of TB that makes up about 1-3% of all cases.
  • Diagnosing it quickly is really important, but traditional methods for testing have some problems, like taking too long and not always being accurate.
  • New tests that look at the DNA of the bacteria causing TB may help diagnose it faster and more accurately, but more studies are needed to figure out how well these tests work and to find ways to improve them.
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This editorial critically explores the use of ankle thigh tourniquets in foot and ankle surgery based on a recent study that found no significant difference in postoperative pain between the two placement techniques. Despite these findings, we argue for the preferential use of ankle tourniquets, highlighting their potential benefits in reducing venous blood stasis and minimizing soft tissue injury. This approach underscores the importance of considering long-term patient outcomes and vascular health beyond immediate postoperative pain.

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Article Synopsis
  • Soft-tissue chondromas are uncommon, benign tumors found mainly in the extremities, often diagnosed in middle-aged individuals, and can be tough to identify due to their slow growth and similarity to other tumors.
  • A case study highlights a 27-year-old male with a painful, enlarging mass on his toe, which underwent various diagnostic imaging techniques before being surgically removed and identified as a soft-tissue chondroma.
  • Proper diagnosis and management are essential, as these tumors, while benign, can significantly affect a person's quality of life and may require careful evaluation to avoid unnecessary treatments.
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Introduction: Needlestick and sharps injuries (NSSIs) represent an existential occupational hazard risk to orthopaedic surgeons during their career due to the interaction with various devices, instruments and bone fragments. Consequently, NSSIs have the potential to transmit infections such as Hepatitis B (HBV), Hepatitis C (HCV) and Human Immunodeficiency Virus (HIV) leading to serious illness. The purpose of this cross-sectional study was to identify the clinical settings predisposing orthopaedic surgeons to NSSIs and assess their adherence to safety protocols in the Indian context.

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Introduction: Proximal tibiofibular joint (PTFJ) subluxations are rare and can occur following trauma or sporting events. Idiopathic PTFJ subluxations are more common in females and in patients with generalized ligament laxity. The proper history and clinical examination together with imaging can help in establishing the diagnosis in the majority of cases.

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The integration of WhatsApp, a widely-used instant messaging application (IMA), into the realm of orthopaedics and trauma surgery has emerged as a significant development in recent years. This paper explores the multifaceted role of WhatsApp in orthopaedics, focusing on its clinical and non-clinical applications, advantages, disadvantages, and future prospects. The study synthesizes findings from various research papers, emphasizing the growing reliance on mobile technology in healthcare.

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Knees are the most commonly impacted weight-bearing joints in osteoarthritis (OA), affecting millions of people worldwide. With increasing life spans and obesity rates, the incidence of knee OA will further increase, leading to a significant increase in the economic burden. Conventional treatment modalities utilized to manage knee OA have limitations.

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In the era of wearable electronic devices, which are quite popular nowadays, our research is focused on flexible as well as stretchable strain sensors, which are gaining humongous popularity because of recent advances in nanocomposites and their microstructures. Sensors that are stretchable and flexible based on graphene can be a prospective 'gateway' over the considerable biomedical speciality. The scientific community still faces a great problem in developing versatile and user-friendly graphene-based wearable strain sensors that satisfy the prerequisites of susceptible, ample range of sensing, and recoverable structural deformations.

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Surgical site infections (SSI) following total joint arthroplasty pose a significant concern for both providers and patients across the globe. Currently, administration of antimicrobial antibiotic prophylaxis is used throughout the world to reduce the incidence of SSI. However, the correct dosage and frequency of administration remains debatable.

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Purpose: This study analyses the performance and proficiency of the three Artificial Intelligence (AI) generative chatbots (ChatGPT-3.5, ChatGPT-4.0, Bard Google AI®) and in answering the Multiple Choice Questions (MCQs) of postgraduate (PG) level orthopaedic qualifying examinations.

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Background: Peroneus longus tendon (PLT) is a known graft utilised in the ligamentous reconstructions of knee. The current review was performed to analyze the available evidence regarding PLT in the arthroscopic anterior cruciate ligament (ACL) reconstruction.

Methods: A comprehensive search of literature was performed on March 1, 2023 using 5 databases (for manuscripts published between 2010 and 2023).

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