Publications by authors named "Vivien Uyen Doan"
Article Synopsis
- A specific genetic risk gene linked to Alzheimer's disease (AD) is overexpressed in patients, but its role in the disease progression remains unclear.
- Researchers used a LC-MS/MS method to analyze brain heparan sulfate (HS) and found a sevenfold increase of a specific 3-sulfated HS in AD patients compared to other tauopathies.
- The study suggests that the overexpression of the genetic risk gene may facilitate tau pathology spread by affecting tau cellular uptake, pointing to a new potential therapeutic target for Alzheimer's disease.
