Publications by authors named "Vivien Tham"

Article Synopsis
  • The study aimed to explore the relationship between weather variables and various pathogens linked to infectious conjunctivitis globally.
  • Researchers analyzed data from 498 cases across 8 countries, correlating pathogen types with weather data, particularly looking at temperature, precipitation, and humidity.
  • Findings indicated that higher humidity and precipitation increased the likelihood of RNA virus and fungal infections while decreasing the odds of DNA virus and bacterial infections, highlighting the complex influence of weather on conjunctivitis-related pathogens.
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Importance: Acute infectious conjunctivitis is a common ocular condition with major public health consequences.

Objective: To assess regional variations and microbial etiologies of acute infectious conjunctivitis to guide treatment.

Design, Setting, And Participants: In this cross-sectional study, patients with presumed acute infectious conjunctivitis were enrolled in the study at 5 sites (Honolulu, Hawaii; Los Angeles, San Francisco, and San Diego, California; and Petah-Tikva, Israel) from March 2021 to March 2023.

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Importance: Common pathophysiological mechanisms may be responsible for immune dysregulation in both thyroid disease and uveitis. Studies investigating a possible association are limited.

Objective: To determine the association between thyroid disease and uveitis.

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Importance: With the increased use of data from electronic medical records for research, it is important to validate International Classification of Diseases, Ninth Revision (ICD-9) codes for their respective diagnoses.

Objective: To assess the accuracy of using ICD-9 codes to identify ocular inflammatory diseases.

Design, Setting, And Participants: Retrospective secondary database analysis.

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Purpose: To assess whether cigarette smoking is associated with the development of uveitis in a population-based setting.

Design: Retrospective, population-based, case-control study.

Participants: Patients aged ≥ 18 years who were seen at a Kaiser Permanente Hawaii clinic between January 1, 2006, and December 31, 2007.

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Purpose: To assess whether there is a protective association between statin use and uveitis diagnosis.

Design: Retrospective, population-based case-control study.

Methods: Medical records of all patients in the Kaiser Permanente Hawaii health plan between January 1, 2006 and December 31, 2007 (N = 217 061) were searched electronically for International Classification of Diseases, 9th Revision, diagnosis codes related to uveitis.

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Importance: Immune dysregulation in patients with atopy has been hypothesized to increase susceptibility to viral infections. Herpetic eye disease (due to herpes simplex and herpes zoster) is a significant cause of visual impairment, and data on an association between this sight-threatening disease and atopy are limited.

Objective: To assess the association between atopy and herpetic eye disease, including herpes simplex virus (HSV) ocular disease and herpes zoster ophthalmicus (HZO).

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Importance: Uveitis is responsible for a significant proportion of legal blindness in the United States. Currently, there are few population-based reports characterizing the epidemiology of uveitis.

Objective: To ascertain the incidence and prevalence of uveitis in a Hawaiian population and compare these estimates with those from prior population-based studies.

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Purpose: To ascertain the incidence of scleritis and episcleritis in a Hawaiian population and describe variations by age, sex, and race.

Design: Retrospective, population-based cohort study.

Methods: All electronic medical records for enrollees in Kaiser Permanente Hawaii (n = 217,061) from January 1, 2006 to December 31, 2007 were searched for International Classification of Diseases, 9th Edition (ICD-9) codes associated with ocular inflammation.

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Purpose: To provide a population-based estimate of the incidence of herpes zoster ophthalmicus (HZO) with comparisons across racial, sex, and age groups, as well as to estimate the frequency of postherpetic neuralgia (PHN).

Design: Retrospective, population-based cohort study.

Participants: All patients enrolled in the Kaiser Permanente Hawaii health plan during the study period (N = 217 061).

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Purpose: To histologically evaluate the outcome of mucous membrane grafts to the eyelid.

Methods: Case series of 31 eyes from 24 patients who underwent transplantation of hard palate (25 eyes), buccal (1 eye), or nasal turbinate (5 eyes) mucosa to the posterior eyelid surface. These grafts were biopsied at 0.

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