Speaker overestimation of communication effectiveness and fear of negative evaluation: being realistic is unrealistic.

Speakers systematically overestimate their communication effectiveness (Keysar & Henly, 2002). We argue that doing so is adaptive, reducing the risk of social anxiety and withdrawal from social situations. This hypothesis was tested by having speakers who scored low and high for fear of negative evaluation (FNE), a hallmark of social phobia, attempt to convey a specific meaning of ambiguous statements to a listener and then estimate their communication effectiveness.

Failure to confirm HIV infection in two end-stage HIV/AIDS patients using a popular commercial line immunoassay.

Immunoassays using either viral lysate (Western blot) or recombinant/synthetic antigen (immunoblot) for anti-HIV capture are still the preferred method to confirm HIV infection. Two cases of HIV-1-infected patients presented with acquired immunodeficiency syndrome (AIDS)-defining illnesses. Laboratory tests were performed using multiple commercial HIV test kits on multiple sera from both patients over several weeks.