Introduction: COVID-19 claimed millions of lives, mainly in the pre-vaccine era. Preliminary studies showed promising efficacy of convalescent plasma against SARS-CoV-2 (CP).
Objective: To evaluate the efficacy of CP in patients hospitalized for COVID-19 with moderate severity.
Background: Philadelphia negative myeloproliferative neoplasms (Ph-MPN) are clonal disorders whose pathogenesis has been elucidated in recent years, creating diagnostic and prognostic algorithms.
Aim: To study JAK2, CALR y MPL gene mutations in patients with Ph-MPN.
Materials And Methods: Descriptive cross-sectional observational study of patients with MPN (2015-2019), reviewing clinical, demographic and laboratory data.
Background: Philadelphia-negative myeloproliferative neoplasms (Ph-MPN) are chronic hematological disorders characterized by the overproduction of one or more mature myeloid blood cell lineages. Classical Ph-MPN are polycythemia vera (PV), essential thrombocytopenia (ET) and primary myelofibrosis (PMF).
Aim: To assess the epidemiological, clinical and diagnostic characteristics of Ph-MPN in Chile.
The coronavirus disease 2019 (COVID19) pandemic has left researchers scrambling to identify the humoral immune correlates of protection from COVID-19. To date, the antibody mediated correlates of virus neutralization have been extensively studied. However, the extent that non-neutralizing functions contribute to anti-viral responses are ill defined.
View Article and Find Full Text PDFBackground: Hodgkin lymphoma has a high rate of curability, even in advanced stages.
Aim: To assess the results of Hodgkin lymphoma treatment using the ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine) chemotherapy regimen.
Material And Methods: Analysis of a database held by the Chilean Ministry of Health, including all patients treated at accredited cancer treatment centers.