Clinical features of muscle stiffness in 37 dogs with concurrent naturally occurring hypercortisolism.

Background: Severe muscle stiffness (SMS) in dogs with hypercortisolism (HC) is uncommon.

Objectives: To evaluate signalment, presentation, treatments, and long-term outcomes of dogs with concurrent HC and SMS.

Animals: Thirty-seven dogs.

Comparison of methods to monitor dogs with hypercortisolism treated with trilostane.

Background: The use of adrenocorticotropic hormone stimulation test as method to monitor efficacy of trilostane treatment of hypercortisolism (HC) in dogs has been questioned.

Objectives: To evaluate and compare 12 methods with which to monitor efficacy of trilostane treatment in dogs with HC.

Animals: Forty-five client-owned dogs with HC treated with trilostane q12h.

Supplementation of omega-3 and dietary factors can influence the cholesterolemia and triglyceridemia in hyperlipidemic Schnauzer dogs: A preliminary report.

Primary hyperlipidaemia in Schnauzer is characterized by increased plasma triglycerides (TG) and/or total cholesterol (TC) concentration and is associated with an increased risk of developing pancreatitis, insulin resistance and seizures. In humans, omega-3 fatty acids in addition to a low-fat diet can be used to reduce TG and TC. This study evaluated the therapeutic efficacy of omega-3 fatty acids associated to a diet management with two different fat content in Schnauzer with primary hyperlipidaemia.

An activating mutation in the CRHR1 gene is rarely associated with pituitary-dependent hyperadrenocorticism in poodles.

Objectives: Pituitary-dependent hyperadrenocorticism is the most common cause of naturally occurring hypercortisolism in dogs. CRHR1 expression in human and dog corticotrophinomas suggested that this gene affects pituitary tumorigenesis. The present study aimed to investigate mutations in the CRHR1 coding region in poodles with pituitary-dependent hyperadrenocorticism.