Publications by Viviane L Simomura

Publications by authors named "Viviane L Simomura"

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and parthenolide increase defensive agents and promote antisecretory activity supporting their gastroprotective actions in rodents.

Cleidiane V Ferraz Amanda M Steffler Cristian A Dalla Vecchia Daniela Miorando Juliana C Maccagnan Viviane L Simomura

Nat Prod Res

November 2024

Article Synopsis

The study investigates the anti-ulcer effects of hydroalcoholic extract (HETp) and its active component parthenolide (PTL) against gastric ulcers induced by ethanol and piroxicam.
Results showed that both HETp and PTL significantly reduced ulcer formation, with additional histological support confirming their effectiveness.
The protective effects involve various mechanisms, including the influence of nitric oxide, adrenergic receptors, and prostaglandins, while also enhancing antioxidant levels and reducing harmful enzyme activity.

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Gastroprotective role of a flavonoid-rich subfraction from Fridericia chica (Bonpl.) L. G. Lohmann: a medicinal plant used in the Amazon region.

Daniela Miorando Amanda M Steffler Cristian A Dalla Vecchia Viviane L Simomura Jaqueline J Veloso

Inflammopharmacology

October 2024

Fridericia chica is an Amazonian plant used to treat stomach disorders. However, the pharmacological activity of flavonoids in the extract has yet to be investigated. Therefore, we considered that a flavonoid-rich F.

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Aqueous extract of the bark of Uncaria tomentosa, an amazonian medicinal plant, promotes gastroprotection and accelerates gastric healing in rats.

Viviane Lazari Simomura Daniela Miorando Beatriz Monteiro Magalhães de Oliveira Aline Mânica Lilian Caroline Bohnen

J Ethnopharmacol

March 2024

Ethnopharmacological Importance: Uncaria tomentosa Willd. DC., is used in the Amazonian region of South America, wherein ethnic groups use the plant to treat diseases, including gastric disorders.

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