Publications by authors named "Viviana Lotero"
Background: Measures to control COVID-19 transmission disrupted childhood cancer care. Data on the effects of the COVID-19 pandemic on childhood cancer mortality are lacking. This study describes the impact of the pandemic on childhood cancer early-mortality (≤ 24 months).
View Article and Find Full Text PDFIntroduction: Acute myeloid leukemia is a challenging disease, due to a poor prognosis in developing countries. Herein, we aim to describe the clinical characteristics and outcomes after chemotherapy and transplantation.
Methods: A retrospective analytic observational study was performed with patients under 18 years of age with newly diagnosed acute myeloid leukemia treated at a referral center in Colombia.
Background: Hemophagocytic lymphohistiocytosis (HLH) is an exaggerated inflammatory reaction secondary to a host's inadequate immune response causing a self-perpetuating loop of altered regulation. Signs and symptoms of HLH are compatible with other common diseases and are nonspecific. Underdiagnosis makes it difficult to estimate the real incidence of HLH, especially in developing countries.
View Article and Find Full Text PDFArticle Synopsis
- Hepatoblastoma is the most common liver tumor in children, typically diagnosed by age 3, with survival rates improving by 50% due to better treatment methods like chemotherapy and surgery.
- A retrospective study on 16 pediatric patients revealed that those undergoing liver resection had a 100% survival rate after 30 months, compared to 65% for those who received liver transplants; most patients had elevated α-fetoprotein levels and required chemotherapy.
- This study is significant as it represents the first report on hepatoblastoma treatments in Colombia and Latin America, supporting the effectiveness of surgical interventions for improving survival outcomes in young patients.