[Factors associated with the perception of discrimination: ageism and quality of life of the geriatric population from a bioethical approach].

Introduction: There are a set of conditions that directly affect the quality of life of older adults, causing marginalization and discrimination of this age group.

Objective: Determining the factors that affect the perception of discrimination and quality of life of older adults in the province of El Oro, Ecuador.

Methods: Observational, descriptive, qualitative-phenomenological, cross-sectional, cross-sectional study in older adults aged 65 years, between September 2019 and November 2020.

Application of crustacean chitin as a co-diluent in direct compression of tablets.

A "simplex-centroid mixture design" was used to study the direct-compression properties of binary and ternary mixtures of chitin and two cellulosic direct-compression diluents. Native milled and fractioned (125-250 microm) crustacean chitin of lobster origin was blended with microcrystalline cellulose, MCC (Avicel PH 102) and spray-dried lactose-cellulose, SDLC Cellactose (composed of a spray-dried mixture of alpha-lactose monohydrate 75% and cellulose powder 25%). An instrumented single-punch tablet machine was used for tablet compactions.

Direct compression properties of chitin and chitosan.

Deformation and compaction properties of native amino poly-saccharides chitin and chitosan were studied and compared with those obtained with established pharmaceutical direct compression excipients. An instrumented single-punch tablet machine was used for tablet compaction. The following compression parameters were evaluated: a ratio of crushing strength and compression pressure, plasticity and elasticity factor (PF and EF), tensile strength and R-value.