Worldwide vaccine inequality threatens to unleash the next COVID-19 variant.

The emergence of the Omicron variant (B.1.1.

Conquering COVID: How Global Vaccine Inequality Risks Prolonging the Pandemic.

The development of effective vaccines during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been deemed a towering achievement in modern science. Since the end of 2020, the vaccine rollout has offered the promise of vanquishing the pandemic in the United States and other developed countries. Even as the United States and other wealthier nations encounter both setbacks and successes in their coronavirus disease 2019 (COVID-19) eradication efforts, developing countries around the world are likely to face far less fortunate fates.

Pancreatitis and Acute Liver Failure From Coricidin® HBP Intoxication.

The use of over-the-counter medications as recreational drugs of abuse in adolescents is increasing. We present the case of a patient who presented with abdominal pain after the ingestion of Coricidin®, an over-the-counter cold medication that contains acetaminophen, chlorpheniramine maleate, and dextromethorphan hydrobromide. The case was complicated by acute liver failure and concomitant pancreatitis that, in a few reported cases, has been associated with high doses of acetaminophen.

A Neonate With Annular Cutaneous Lesions.

Neonatal lupus erythematosus is a rare disorder with a wide spectrum of clinical presentations. The disease can affect several systems, including the skin, heart, liver, and bone marrow. Thus, a recognition of its different presentations is vital for making a diagnosis.

Elvitegravir: a once-daily inhibitor of HIV-1 integrase.

Introduction: Elvitegravir (EVG) is a potent inhibitor of HIV-1 integrase (IN) undergoing Phase III clinical trials. It blocks the strand-transfer step in a multi-step process that allows double-stranded cDNA to be irreversibly incorporated within the host DNA. It is the second member of the HIV-1 IN inhibitor class, following raltegravir.