Effects of a nutritional supplement fortified with vitamin B-12 on well nourished, free-living elderly subjects.

Unlabelled: Vitamin B-12 deficiency is prevalent among the elderly population but it is often unrecognized because the clinical manifestations are not present.

Objective: To evaluate the effects of a nutritional supplement fortified with vitamin B-12 on well nourished, free-living elderly subjects.

Patients And Methods: Healthy elderly subjects attending two of four clinics were allocated to receive, over six months' duration, a nutritional supplement with 3.

Long-term nutritional and digestive consequences of pelvic radiation.

Objective: To study long-term changes in nutritional status and gastrointestinal (GI) functions of 15 women previously treated with radiotherapy for gynecological cancer. Two years prior to this research, these patients had been assessed twice: before external radiotherapy and 5 weeks later, at the completion of the external dose (45-50 Gy).

Methods: Each patient was given complete clinical evaluation, consisting of dietary, physical activity and digestive symptoms questionnaires.

Hyperhomocysteinemia and endothelial function in young subjects: effects of vitamin supplementation.

Background: The relationship between hyperhomocysteinemia and cardiovascular disease has not been totally elucidated.

Hypothesis: The study aimed to verify the association between hyperhomocysteinemia and endothelial dysfunction before and after modification of total homocysteine (tHcy) serum levels with vitamin supplementation in young male subjects devoid of any other cardiovascular risk factor.

Methods: Twenty hyperhomocysteinemic (tHcy > 15 [micromol/l) male volunteers (< or = 40 years) and 20 age-matched subjects with normal tHcy levels (tHcy < 13 micromol/l) were included.

The Chilean flour folic acid fortification program reduces serum homocysteine levels and masks vitamin B-12 deficiency in elderly people.

Hyperhomocysteinemia is considered a risk factor for cardiovascular disease and is prevalent in the elderly. Supplementation with folic acid, vitamin B-6 and B-12 lowers homocysteine levels. In January 2000, the Chilean government initiated a flour folic acid fortification program to decrease the occurrence of neural tube defects.