Objective: This study aimed to analyze the impact of contraceptives on medical students at the Federal University of Paraná and verify adherence, consequences, and lifestyle effects of the contraceptive method used.
Methods: This is an observational, cross-sectional study in which 214 participants answered an online questionnaire composed of 30 questions. For statistical analysis, the Stata® 16.
PLoS One
January 2022
Background: The diagnosis of mood disorders (MD) during pregnancy is challenging and may bring negative consequences to the maternal-fetal binomial. The long waitlist for specialized psychiatric evaluation in Brazil contributes to the treatment omission. Almost 20.
View Article and Find Full Text PDFBackground: Global surgery is an interdisciplinary field that advocates for access to equitable, affordable surgical services for all people. Engaging medical students in the field can strengthen the surgical workforce in low- and middle-income countries. We aim to investigate Brazilian medical students' acknowledgment of global surgery and their preferred learning platforms.
View Article and Find Full Text PDFIntroduction: Uterine leiomyomas are the most common benign pelvic tumors in women over 35 years and can be symptomatic or asymptomatic. Among the main treatment strategies, there are hormone therapy, hysterectomy, myomectomy, and uterine artery embolization (UAE), a recent and promising treatment for patients who wish to avoid hysterectomy. Ideal candidates for UAE are women with symptomatic uterine leiomyomas that present no desire for pregnancy, premenopausal and heavy menstrual bleeding, or dysmenorrhea caused by intramural fibroids.
View Article and Find Full Text PDFBackground: Low back pain can be caused by several pathological entities and its perception can be altered by external factors, for example by some psychological and social factors. The objective of this study was to compare surgical outcomes in patients with or without psychosocial issues.
Methods: Single center, retrospective and comparative study.
To evaluate the effect of mesenchymal stem cells (MSCs) on fertility in experimental retrocervical endometriosis. A total of 27 New Zealand rabbits were divided into three groups: endometriosis, in which endometrial implants were created; mesenchymal, in which MSCs were applied in addition to the creation of endometrial implants; and control, the group without endometriosis. Fisher's exact test was performed to compare the dichotomous qualitative variables among the groups.
View Article and Find Full Text PDFRev Bras Cir Cardiovasc
September 2015
Introduction: Acute myocardial infarction is a social health problem of epidemiological relevance, with high levels of morbidity and mortality. Stress is one of the modifiable risk factors that triggers acute myocardial infarction. Stress is a result of a set of physiological reactions, which when exaggerated in intensity or duration can lead to imbalances in one's organism, resulting in vulnerability to diseases.
View Article and Find Full Text PDFIntroduction: Most cardiomyocytes do not regenerate after myocardial infarction. Porcine small intestinal submucosa has been shown to be effective in tissue repair.
Objective: To evaluate myocardial tissue regeneration and functional effects of SIS implantation in pigs after left ventriculotomy.
Objective: To analyze the functional and anatomical-pathological effect of transplantation of bone marrow mononuclear cells associated to aquatic physical activity after myocardial infarction in rats.
Methods: Twenty-one rats were induced by myocardial infarction, through left coronary artery ligation. After a week, the animals were subjected to echocardiography for evaluation of left ventricle ejection fraction (LVEF, %) and dyastolic and end systolic volume of the left ventricle (EDV, ESV, ml), randomized and the transplantation of mononuclear stem cells.
Background: Myocardial infarction is a public health problem. Functional food is an alternative treatment for cardiovascular diseases.
Objective: The objective was to analyze the functional and anatomopathological post-myocardial-infarction effects of soybean extract (SE) and isoflavone (IF).
Clin Rehabil
November 2012
Objective: To compare models of the postoperative hospital treatment phase after myocardial revascularization.
Design: A pilot randomized controlled trial.
Setting: Hospital patients in a hospital setting.
Objective: To evaluate the effect of anti-TNF-α in the treatment of endometrial implants in the peritoneum of rats.
Methods: Endometrial implants were surgically induced in 120 female Wistar-Albino rats. The animals were randomly divided into four groups.
Eur J Obstet Gynecol Reprod Biol
October 2011
Objective: Endometriosis is a multifactorial disease of uncertain etiology. There is currently insufficient evidence to assess the participation of nutritional and anthropometric aspects and their association with systemic oxidative stress.
Study Design: Twenty-five women with endometriosis and twenty controls were selected and evaluated to determine calorie and nutrient intake, to obtain data on body composition and analyze antioxidant capacity by measuring total serum thiol levels using DTNB (5,5'-dithiobis-(2-nitrobenzoic acid).
Eur J Obstet Gynecol Reprod Biol
October 2011
Objective: To study the effect of bone marrow derived-mononuclear stem cells transplantation in the growth, VEGF-R and TNF-alpha expression of surgically induced endometriosis in an experimental model.
Study Design: This is an experimental study conducted in the Center for Health and Biological Sciences at the Pontifical Catholic University of Parana, Brazil. Endometriotic implants were surgically induced in 120 female Wistar rats.
Introduction And Hypothesis: The objective of this study was to evaluate the prevalence of urinary incontinence (UI), the pelvic floor, and the quality of life during pregnancy and in the postpartum.
Methods: Three hundred and forty-three women in the third trimester of pregnancy were submitted to physiotherapeutic evaluation for UI and evaluation of pelvic floor muscle function and were asked to fill out the King's Health Questionnaire (KHQ). Of these, 236 returned for postpartum evaluation (65.
Objectives: To develop an experimental model of endometriosis in rats.
Methods: Thirty adult female Wistar rats were used. The surgical technique consisted of median laparotomy with identification of the bicornuate uterus and resection of a 2-cm segment of the right uterine horn.
A 69-year-old woman presented with white papules on her neck. These papules were multiple, white, discrete, asymptomatic, non-follicular, 2 to 3 mm in diameter, and located on both sides of the neck. On histopathological examination, there was a thickened and abnormal organization of collagen bundles in the papillary to mid-dermis and a decrease in the number of elastic fibers.
View Article and Find Full Text PDFContext And Objective: Diagnoses of endometriosis are based on observation of endometriotic lesions by means of laparoscopy, along with the pathological findings. The aim of this study was to evaluate the sensitivity and specificity of the macroscopic findings in relation to the histopathological findings. More specifically, we aimed to test the efficacy of laparoscopy alone for diagnosing endometriosis and to evaluate the laterality of endometriosis among the study population.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
January 2009
Objective: To assess depressive symptoms, anxiety and quality of life in women with pelvic endometriosis.
Study Design: A prospective study of 104 women diagnosed with pelvic endometriosis. The Beck Depression Inventory (BDI) and the Hamilton Rating Scale for Depression (HAM-D) were used to evaluate depressive symptoms; the Spielberger State-Trait Anxiety Inventory (STAI) and the Hamilton Rating Scale for Anxiety (HAM-A) to evaluate anxiety symptoms; and the short (26-item) version of the World Health Organization Quality Of Life instrument (WHOQOL-BREF) to evaluate quality of life.
Context And Objective: One of the diagnostic markers of endometriosis is CA-125, and elevated levels of this are caused by high concentrations in the ectopic endometrium. The objective of this study was to correlate CA-125 levels in serum and peritoneal fluid from women with and without pelvic endometriosis.
Design And Setting: This was a prospective, cross-sectional, controlled study of consecutive patients undergoing laparoscopy for infertility, pelvic pain or tubal ligation, during early follicular phase, at the university hospital of Faculdade de Medicina de Ribeirão Preto.
Eur J Obstet Gynecol Reprod Biol
March 2005
Objective: To assess the level of lipid peroxidation in the peritoneal fluid of infertile women with peritoneal endometriosis and of fertile disease-free controls.
Study Design: Level of lipid peroxidation (malondialdeyde, malondialdeyde with copper addition, and cholest-3,5-dien-7-one) was measured in the peritoneal fluid obtained from 21 women with endometriosis-related infertility and from 21 fertile women having tubal ligation.
Results: : The level of lipid peroxidation did not differ significantly (P > 0.