Publications by authors named "Vivi Sofia"

Ulva lactuca L. contains bioactive substances with anti-inflammatory, antibacterial, and antioxidant properties that aid in healing cut wounds. This research was done to ascertain the histopathological parameter's effects on the wound-healing capacity of gels made from the ethanol extract of U.

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Background: Pharmacological therapy in the management of OA causes many new health problems due to side effects caused by long-term use of drugs, such as long-term use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) will cause gastric ulcers and impaired kidney function. In OA pathogenesis, gene is involved in the inflammation process.

Aim: This study aims to identify the influence of Wharton Jelly Mesenchymal Stem Cell (MSC-WJ) on expression gene in synoviocyte by in vitro.

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Background: Therapy for osteoarthritis (OA) with satisfactory results has not been found to date. In OA pathogenesis, gene involved in cartilage degradation and MMP-13 in degrade cartilage, as a member family of NF-κβ genes, serves to modulate inflammatory responses and activates pro-inflammatory cytokines.

Aim: This study aims to identify the influence of Wharton Jelly Mesenchymal Stem Cell (MSC-WJ) on and expression gene in synoviocyte by in vitro.

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Background: Therapy that can cure osteoarthritis with satisfactory results has not been found to date. In the pathogenesis of osteoarthritis, the genes involved in cartilage degradation include the gene which plays an important role in modulating the occurrence of cartilage damage, which involves activation of pro-inflammatory cytokines. One of the cytokines involved in the cartilage degradation process is Matrix Metalloproteinase (MMP) -13 which is also modulated by NFκβ.

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