Publications by authors named "Vivek Ily"
Neuropharmacology
January 2025
Article Synopsis
- Alcohol use disorder (AUD) is linked to binge drinking and can cause lasting changes in the brain's neurocircuitry, particularly in the extended amygdala, leading to neuroinflammation and potential relapse.
- A study using the Drinking in the Dark (DID) model in rodents found that the anti-inflammatory drug minocycline reduced binge drinking behavior without significantly affecting long-term consumption of natural rewards like food and water.
- The research also highlighted significant changes in microglia morphology in the central amygdala but not in the basolateral amygdala, indicating that targeting neuroinflammation could be a promising approach for treating AUD.
