Publications by authors named "Vittoria Ardito"

Background: There is a growing enthusiasm for machine learning (ML) among academics and health care practitioners. Despite the transformative potential of ML-based applications for patient care, their uptake and implementation in health care organizations are sporadic. Numerous challenges currently impede or delay the widespread implementation of ML in clinical practice, and limited knowledge is available regarding how these challenges have been addressed.

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Article Synopsis
  • The study examines various pricing and payment schemes for healthcare technologies to address issues of affordability and access, highlighting a lack of clear categorization for these schemes.
  • A systematic literature review was conducted to identify and detail 70 unique pricing and payment schemes, revealing that a significant portion are not explicitly tied to specific therapeutic areas.
  • The authors propose a flexible, need-driven classification approach for these schemes, focusing on their unique characteristics rather than fitting them into a strict taxonomy.
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  • The study compares the use of Impella pumps and VA-ECMO in treating patients with cardiogenic shock, focusing on clinical outcomes, resource use, and quality of life.
  • Conducted across 17 clinical centers in Italy, the research involves both prospective data collection for Impella patients and retrospective data matching for VA-ECMO patients to assess cost-effectiveness and budget impact.
  • As of May 2024, most centers have received ethical approval for the study, with plans to publish results in peer-reviewed journals for wider dissemination.
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Introduction: Innovative pricing and payment/reimbursement schemes have been proposed as one part of the solution to the problem of patient access to new health technologies or to the uncertainty about their long-term effectiveness. As part of a Horizon Europe research project on health innovation next generation pricing and payment models (HI-PRIX), this protocol illustrates the conceptual and methodological steps related to a scoping review aiming at investigating nature and scope of pricing and payment/reimbursement schemes applied to, or proposed for, existing or new health technologies.

Methods: A scoping review of literature will be performed according to the PRISMA guidelines for scoping reviews (PRISMA-ScR) guidelines.

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  • * The study aims to implement a new patient-centered care pathway that involves a collaborative team of healthcare professionals to better address the needs of these older patients.
  • * Conducted as a multicentric trial across Europe, the GERONTE study will compare the outcomes of patients receiving this new care approach with those who receive standard oncologic care.
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Despite the acceleration in the use of digital health technologies across different aspects of the healthcare system, the full potential of real-world data (RWD) and real-world evidence (RWE) arising from the technologies is not being utilised in decision-making. We examine current national efforts and future opportunities to systematically use RWD and RWE in decision-making in five countries (Estonia, Finland, Germany, Italy and the United Kingdom), and then develop a framework for promotion of the systematic use of RWD and RWE. A review assesses current national efforts, complemented with a three-round consensus-building exercise among an international group of experts (1 = 44, 2 = 24, 3 = 24) to derive key principles.

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Background: An increasing interest in machine learning (ML) has been observed among scholars and health care professionals. However, while ML-based applications have been shown to be effective and have the potential to change the delivery of patient care, their implementation in health care organizations is complex. There are several challenges that currently hamper the uptake of ML in daily practice, and there is currently limited knowledge on how these challenges have been addressed in empirical studies on implemented ML-based applications.

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Background: Shared decision-making (SDM) is a collaborative process whereby patients and clinicians jointly deliberate on the best treatment option that takes into account patients' preferences and values. In breast cancer care, different treatment options have become available to patients in the last decade. Various interventions, including patient decision aids (PtDAs), have been designed to promote SDM in this disease area.

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Impella and VA-ECMO are two possible therapeutic courses for the treatment of patients with cardiogenic shock (CS). The study aims to perform a systematic literature review and meta-analyses of a comprehensive set of clinical and socio-economic outcomes observed when using Impella or VA-ECMO with patients under CS. A systematic literature review was performed in Medline, and Web of Science databases on 21 February 2022.

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Background: Mobile health (mHealth) solutions have proven to be effective in a wide range of patient outcomes and have proliferated over time. However, a persistent challenge of digital health technologies, including mHealth, is that they are characterized by early dropouts in clinical practice and struggle to be used outside experimental settings or on larger scales.

Objective: This study aimed to explore barriers and enablers to the uptake of mHealth solutions used by patients with cancer undergoing treatment, using a theory-guided implementation science model, that is, the Consolidated Framework for Implementation Research (CFIR).

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