Detection of glaucomatous optic nerve head by using Heidelberg topographic maps.

Purpose: To evaluate the capacity of a new topographic map analysis to detect abnormal optic discs from healthy ones in a new cohort of subjects.

Patients And Methods: Only one eye was chosen randomly from each subject included in the study. In total, 20 normal eyes with a normal visual field, an IOP of <22 mmHg and no history of glaucoma in their family, and 20 glaucomatous eyes with an abnormal visual field and an open angle were selected.

Correlation between frequency doubling technology and heidelberg retina tomograph.

Purpose: To evaluate the association between Heidelberg Retina Tomograph (HRT) parameters and the Frequency Doubling Technology (FDT) indices in ocular hypertension or primary open angle glaucoma patients.

Methods: One eye was randomly chosen from 85 patients with primary open angle glaucoma (abnormal visual field and/or abnormal optic nerve and untreated IOP > 21 mm Hg) and ocular hypertension (normal visual field and normal optic nerve and untreated IOP > 21 mm Hg). All the patients were examined with Humphrey Perimeter program 30-2 full threshold, FDT program C 20-5, and HRT.

Retinal peripapillary blood flow before and after topical brinzolamide.

Purpose: To study the effect of topical brinzolamide on retinal capillary blood flow by the Heidelberg Retina Flowmeter (HRF) in patients with glaucoma.

Methods: Twenty patients with glaucoma were consecutively recruited. One eye for each patient was randomly selected.

Retinochoroiditis associated with congenital toxoplasmosis in children: IgG antibody profiles demonstrating the synthesis of local antibodies.

Purpose: Retinochoroiditis is generally diagnosed after the first year of life and the association with congenital toxoplasmosis presents a diagnostic dilemma. The detection of local intraocular specific antibodies could be useful for diagnosis.

Methods: We studied six patients (mean age 7 +/- 5 years) with retinochoroiditis which appeared after the first year of life.

Detection of glaucomatous visual field defect by nonconventional perimetry.

Purpose: To report the correlations among Humphrey Field Analyzer 750 (HFA), high-pass resolution perimetry (HRP), and frequency-doubling technology (FDT) perimetry in glaucoma patients and ocular hypertensive patients.

Design: Cross-sectional study.

Methods: Eighty-two eyes of 82 consecutive patients with primary open-angle glaucoma (POAG) or ocular hypertension were included in this study.

Intraobserver reproducibility of a two-dimensional mapping of the optic nerve head perfusion.

Purpose: To evaluate the intraobserver reproducibility of a software designed to assess retinal blood flow with the Heidelberg Retina Flowmeter (HRF).

Methods: Ten subjects were consecutively recruited, and one eye of each patient was randomly selected for study. Blood flow measurements were analyzed by using an automatic full field perfusion image analysis (AFFPIA) program, which calculates the Doppler frequency shift and hemodynamic variables (flow, volume, and velocity) for each pixel.

Pediatric ultrasound: a personal experience during the period 1991-1994.

The ultrasound examination of the eye with A and B scan has become one of the principal diagnostic methods for detecting ocular abnormalities in children because it is a non invasive technique and can be performed without resorting to general anesthesia. The authors report the most unusual and interesting cases from 1,226 examinations performed in the Department of Ophthalmology, Istituto G. Gaslini, Genova, Italy, between January 1991 and December 1994.

A retrospective study of ocular side effects in children undergoing bone marrow transplantation.

Bone marrow transplantation (BMT) is recognized as a successful treatment for malignant and non-malignant hematological diseases. Thanks to transplantation, the number of long-term survivors has risen and with the improved prognosis a problem of ocular side effects has arisen. We carried out a retrospective study to determine the incidence and etiopathogenesis of ocular complications in a series of young patients undergoing BMT.

Neuroblastoma IV-S in a patient with bilateral microphthalmia.

Neuroblastoma, a tumor of post-ganglionic sympathetic neurons, may be associated with a variety of genetic defects and congenital malformations (1). We report a case of neuroblastoma (NB) stage IV-S (2) in an infant with bilateral microphthalmia and other ocular malformations.

Tapioca melanoma of the iris: a contribution to the fine structure and its significance.

A case of iris malignant melanoma, macroscopically classified as tapioca melanoma, was studied by electron microscopy. The tumor originated in the left eye of a patient, and a specimen was obtained during iridociclectomy. Two main types of cells were found: the differences between them concerned mainly the Golgi complex, mitochondria, RER and free ribosomes.