Publications by authors named "Vitoria S Botezelli"

Article Synopsis
  • - The transition of tetrapods to terrestrial ecosystems around 375 million years ago marked a significant evolutionary step, driven by adaptations like the development of a tympanic ear that improved sound detection in air.
  • - Earlier theories claimed a single evolutionary origin for the tympanic ear in tetrapods, but recent studies indicate it evolved independently in amphibians, mammals, and reptiles, though it’s unclear how many times this occurred within reptiles.
  • - New research combines developmental and paleontological insights, suggesting that the tympanic membrane was likely present in a common ancestor of crown reptiles, arguing for a single evolutionary origin rather than multiple instances for tympanic hearing in modern reptiles.
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ASCL1 is a transcription factor that directs neural progenitors towards lineage differentiation. Although many of the molecular mechanisms underlying its action have been described, several of its targets remain unidentified. We identified in the chick genome a putative enhancer (cE1) upstream of the transcription factor () locus with a predicted heterodimerization motif for ASCL1 and POU3F2.

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