Publications by authors named "Vitor Hugo Moreau da Cunha"
J Ethnopharmacol
January 2021
Article Synopsis
- Jatropha curcas L. (known as "Pinhão Manso") is a medicinal plant with potential antimicrobial, antioxidant, and anti-inflammatory properties, particularly relevant in treating neuroinflammatory conditions.
- This study explored the anti-inflammatory effects of a methanolic extract from J. curcas leaves on glial cells from neonate Wistar rats, showing that it did not harm cell viability even at high concentrations.
- The extract significantly inhibited inflammatory responses in glial cells induced by lipopolysaccharide (LPS), reducing morphological changes and the expression of inflammatory markers like GFAP, Iba1, and NF-kB, while also decreasing nitric oxide production.
