Publications by authors named "Vitor Almeida Ribeiro de Miranda"
Article Synopsis
- The study investigated how certain gene variations (polymorphisms) in collagen type I relate to the risk of developing tendinopathy among Brazilian athletes.
- Conducted with 242 athletes (55 with tendinopathy), it identified specific polymorphisms (rs42524 and rs2621215) that significantly increased the likelihood of tendinopathy, particularly in those aged 25 or older and with over 6 years of sports experience.
- Results showed that while some genetic variations elevated the risk, a certain haplotype appeared to reduce the risk of developing the condition.
Background: High levels of the tumor necrosis factor alpha (TNF-α) induce apoptosis and pro-inflammatory effects for primary degeneration of tendon and development of tendinopathy. The aim of this study was to investigate the association between the TNF-α polymorphisms and tendinopathy in athletes.
Methods: Two hundred and seventy athletes (135 tendinopathy cases and 135 controls) were included and genotyped (TNF-α -1031T > C; -857 C > T; -308G > A) using TaqMan validated assays.
Background: Musculoskeletal injuries (MSK-I) are a serious problem in sports medicine. Modifiable and non-modifiable factors are associated with susceptibility to these injuries. Thus, the aim of this study was to describe the prevalence of and identify the factors associated with MSK-I, including tendinopathy and joint and muscle injuries, in athletes.
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