Overweight effect on spirometric parameters in adolescents undergoing exercise.

Objective: To evaluate effects of overweight on spirometric parameters in adolescents who underwent bronchial provocation test for exercise.

Methods: We included 71 male adolescents. The diagnosis of asthma was done based on participants' clinical history and on the International Study Questionnaire Asthma and Allergies in Childhood, and the diagnosis of obesity was based on body mass index above 95th percentile.

Leucine minimizes denervation-induced skeletal muscle atrophy of rats through akt/mtor signaling pathways.

The aim of the present study was to evaluate the effect of leucine treatment (0.30 mM) on muscle weight and signaling of myoproteins related to synthesis and degradation pathways of soleus muscle following seven days of complete sciatic nerve lesion. Wistar rats (n = 24) of 3-4 months of age (192 ± 23 g) were used.