Publications by authors named "Vito G Roque"

Dengue is a mosquito-transmitted virus infection that causes epidemics of febrile illness and hemorrhagic fever across the tropics and subtropics worldwide. Annual epidemics are commonly observed, but there is substantial spatiotemporal heterogeneity in intensity. A better understanding of this heterogeneity in dengue transmission could lead to improved epidemic prediction and disease control.

View Article and Find Full Text PDF

Proper understanding of the long-term epidemiology of chikungunya has been hampered by poor surveillance. Outbreak years are unpredictable and cases often misdiagnosed. Here we analyzed age-specific data from 2 serological studies (from 1973 and 2012) in Cebu, Philippines, to reconstruct both the annual probability of infection and population-level immunity over a 60-year period (1952-2012).

View Article and Find Full Text PDF
Article Synopsis
  • - A study in Cebu City, Philippines from 2012-2013 explored the prevalence of symptomatic and subclinical Chikungunya virus (CHIKV) infections, finding that subclinical cases were much more common, occurring at a ratio of 4.6:1 compared to symptomatic cases.
  • - Of the 853 participants, the study identified 19 symptomatic infections and 87 subclinical infections, with the rate of subclinical infections varying significantly by age.
  • - High baseline CHIKV antibody levels were found to provide complete protection against symptomatic infections, and genetic analysis revealed a close relationship between local strains and those found in Asia and the Caribbean.
View Article and Find Full Text PDF

Background: Japanese encephalitis virus (JEV) is an important cause of encephalitis in most of Asia, with high case fatality rates and often significant neurologic sequelae among survivors. The epidemiology of JE in the Philippines is not well defined. To support consideration of JE vaccine for introduction into the national schedule in the Philippines, we conducted a systematic literature review and summarized JE surveillance data from 2011 to 2014.

View Article and Find Full Text PDF

This literature analysis describes the available dengue epidemiology data in the Philippines between 2000 and 2011. Of 253 relevant data sources identified, 34, including additional epidemiology data provided by the National Epidemiology Center, Department of Health, Philippines, were reviewed. There were 14 publications in peer reviewed journals, and 17 surveillance reports/sources, which provided variable information from the passive reporting system and show broad trends in dengue incidence, including age group predominance and disease severity.

View Article and Find Full Text PDF

Background: Accurate prediction of dengue incidence levels weeks in advance of an outbreak may reduce the morbidity and mortality associated with this neglected disease. Therefore, models were developed to predict high and low dengue incidence in order to provide timely forewarnings in the Philippines.

Methods: Model inputs were chosen based on studies indicating variables that may impact dengue incidence.

View Article and Find Full Text PDF

The World Health Organization's revised International Health Regulations (IHR (2005)) call for member state compliance by mid-2012. Variation in disease surveillance and core public health capacities will affect each member state's ability to meet this deadline. We report on topics presented at the preconference workshop, "The Interaction of Disease Surveillance and the International Health Regulations," held at the 2010 International Society for Disease Surveillance conference in Park City, Utah.

View Article and Find Full Text PDF