Publications by authors named "Vitaly Chagovets"
Article Synopsis
- The COVID-19 pandemic has raised concerns about its indirect effects on pregnant women and the development of their offspring, prompting research into lipid metabolism changes in the "mother-placenta-fetus" system.
- A study involving 234 women analyzed lipid profiles in maternal plasma, cord blood, and amniotic fluid, revealing elevated levels of certain lipids linked to COVID-19 infections, particularly significant during the second trimester.
- The research led to the creation of a diagnostic model for newborns based on maternal lipid profiles, indicating a strong diagnostic value and highlighting the key metabolic disturbances caused by COVID-19 during pregnancy.
Follicular fluid is an important component of follicle growth and development. Negative effects of COVID-19 on follicular function are still open. The aim of this work was to study the features of the lipid profile of follicular fluid and evaluate the results of the in vitro fertilization (IVF) program in women after COVID-19 to identify biomarkers with prognostic potential.
View Article and Find Full Text PDFComparative studies of molecular alterations upon cancer between mice and humans are of great importance in order to determine the relevance of research involving mouse cancer models to the development of diagnostic and therapeutic approaches in clinical practice as well as for the mechanistic studies of pathology in humans. Herein, using molecular fingerprinting by internal extractive electrospray ionization mass spectrometry (iEESI-MS), we identified 50 differential signals in mouse liver tissue and 62 differential signals in human liver tissue that undergo significant intensity alterations (variable importance in the project (VIP) >1.0) upon liver cancer, out of which only 27 were common in both mouse and human tissues.
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