Publications by authors named "Vitaly Bruskov"
Article Synopsis
- Researchers developed a new ligand (called probe 12) based on 4-methoxyphenyl-2,2'-bipyridine that can detect zinc through fluorescence, showing a significant increase in brightness when zinc is present.
- Probe 12 has a high binding affinity for zinc, with a binding constant of approximately 2 × 10^6 M⁻¹ and a limit of detection at around 0.1 nM, outperforming a previously known probe.
- The effectiveness of probe 12 for zinc detection was confirmed through various methods, and it proved capable of identifying zinc in both live cells and fixed tissues, specifically highlighting pancreatic beta cells.
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