Purpose: To identify the clinical features predictive of any optic nerve infiltration and postlaminar optic nerve infiltration by retinoblastoma on histopathology and to report the outcome (metastasis and death) in these patients.
Methods: Retrospective study.
Results: Of the 403 patients who underwent primary enucleation for retinoblastoma, 196 patients had optic nerve tumor infiltration (Group 1) and 207 patients had no evidence of optic nerve tumor infiltration (Group 2).
Purpose: To identify the clinical features predictive of high-risk retinoblastoma on histopathology.
Design: Case-control study.
Participants: A total of 145 cases with histopathologic high-risk features of retinoblastoma and 258 controls without high-risk features.