Antinociceptive effect of botulinum toxin type A on experimental abdominal pain.

Visceral pain, especially in the abdominal region, represents one of the most common types of pain. Its chronic form is usually very hard to treat by conventional analgesic agents and adjuvants. We investigated the antinociceptive effect of botulinum toxin type A (BTX-A) in male Wistar rats in two models of visceral pain: peritonitis induced by intraperitoneal injection of 1% acetic acid and colitis induced by intracolonic instillation of 0.

Worldwide first experiences with vacuum-assisted closure as alternative treatment method to repair defects of an extended thoracic wall recurrence of breast cancer.

Introduction: Loco-regional recurrences of the breast cancer are associated with a bad prognosis. Often costly autologous-tissue treatment as a surgery aiming at repairing the defects is necessary.

Patients And Methods: Four female patients were treated with the vacuum-assisted closure (VAC)-system in context with the recurrence resection.

Worldwide first successful splitting of the breast for a single-procedure reconstruction after mastectomy with maintaining the sensitivity.

Purpose: Breast reconstructions are made autologously, that is with the body's own tissue, or heterologously by means of implants. This either causes donor site morbidity or a foreign body is implanted. Both are disadvantages which could not be avoided up to now.

Urinary and anal incontinence after vacuum delivery.

Objectives: To evaluate urinary and fecal incontinence symptoms, and occult anal sphincter defects in women after vacuum and spontaneous vaginal delivery.

Study Design: In a case-control study, 50 primiparous women delivered by vacuum extraction were compared to 50 women delivered spontaneously. Urinary and anal incontinence symptoms, pelvic floor muscle strength and sphincter defects on endoanal ultrasound were evaluated 6-24 weeks postpartum.