Publications by authors named "Vishwanath Upadhyay"
Article Synopsis
- Long COVID, a condition affecting individuals after recovering from COVID-19, presents a range of symptoms that can persist for weeks to months, regardless of the initial severity of the illness.
- Risk factors for developing long COVID include older age, female gender, and pre-existing health conditions, with symptoms like fatigue, cognitive impairment, and respiratory issues affecting about 10-20% of patients, mainly reported in high-income countries.
- While there are currently no definitive lab tests for diagnosing long COVID, emerging biomarkers and rehabilitation strategies are essential for managing the condition, alongside vaccination and early antiviral treatments to help prevent its onset.
Non-tuberculous mycobacteria: a disease beyond TB and preparedness in India.
Expert Rev Respir Med
July 2021
Background And Methods: Fifty-six Indian studies on NTM diseases were selected between 1981 and 2020 from various electronic databases (PubMed, EMBASE, Medline, BIOSIS preview, and Scopus) for systematic review.
Results: NTM isolation rates increased from 0.9% between 2001 and 2010 to 1.
Epidemiology, diagnosis & treatment of non-tuberculous mycobacterial diseases.
Indian J Med Res
September 2020
Non-tuberculous mycobacteria (NTM) are ubiquitously present in the environment, but NTM diseases occur infrequently. NTM are generally considered to be less virulent than Mycobacterium tuberculosis, however, these organisms can cause diseases in both immunocompromised and immunocompetent hosts. As compared to tuberculosis, person-to-person transmission does not occur except with M.
View Article and Find Full Text PDFBackground & Objectives: The burden of non-tuberculous mycobacterial (NTM) disease is increasing worldwide. The disease shares clinicoradiological features with tuberculosis (TB), Nocardia and several fungal diseases, and its diagnosis is frequently delayed. The present study was performed to determine the frequency of NTM disease among TB suspects in a tertiary care centre in north India.
View Article and Find Full Text PDFBackground: Due to low predictive values of obstructive sleep apnea (OSA) screening tools, there is a need for biomarker for screening of OSA patients at an early stage. The aim of the study was to evaluate differentially expressed proteins in blood and urine samples of OSA patients.
Methods: In this study, we used isobaric tagging for relative and absolute quantification (iTRAQ) based proteomics approach to identify differentially expressed proteins, which were subsequently verified and validated using enzyme-linked immunosorbent assay (ELISA) technique in adult OSA patients.
Narcolepsy is a common sleep disorder in Western countries but rarely reported from India. Here, we report a small case series of four narcolepsy patients seen over a four year period in the sleep clinic of a tertiary care hospital in north India. The diagnosis was established by clinical history and two or more sleep-onset rapid eye movements (SOREMs) on multiple sleep latency tests (MSLTs) following overnight polysomnography (PSG).
View Article and Find Full Text PDFBackground & Objectives: The N-acetyltransferase 2 (NAT2) gene encodes an enzyme which both activates and deactivates arylamine and other drugs and carcinogens. This study was aimed to investigate the role of NAT2 gene polymorphism in anti-tuberculosis drug-induced hepatotoxicity (DIH).
Methods: In this prospective study, polymerase chain reaction-restriction fragment length polymorphism results for NAT2 gene were compared between 185 tuberculosis patients who did not develop DIH and 105 tuberculosis patients who developed DIH while on anti-tuberculosis drugs.