Drug-Induced Aseptic Meningitis Associated With Intrathecal Trastuzumab.

To report a case of drug-induced aseptic meningitis (DIAM) in a patient receiving intrathecal trastuzumab (ITT) for leptomeningeal carcinomatosis (LC) secondary to HER-2/neu positive breast cancer. A 43-year-old female with stage IV breast cancer presented with headache, parasthesias, and aphasia. Brain imaging suggested leptomeningeal enhancement.

Bone health management in prostate cancer patients receiving androgen deprivation therapy.

Purpose: Patients receiving androgen deprivation therapy undergo a rapid decline in bone mineral density during the first 6 to 12 months of initiating therapy. The World Health Organization has developed and implemented the Fracture Risk Assessment Tool (FRAX) to predict the ten year risk of a major fracture & hip fracture. Additionally, the National Comprehensive Cancer Network and the National Osteoporosis Foundation have developed osteoporosis guidelines.

Effect of "energy drink" consumption on hemodynamic and electrocardiographic parameters in healthy young adults.

Background: Energy drinks are frequently purported to improve cognitive function and concentration. However, the cardiovascular effects of these drinks have not been adequately studied.

Objective: To determine the cardiac effects of a commercially available, multicomponent energy drink in healthy volunteers.