Publications by authors named "Vishnuppriya C"
Performance Comparison between Deep Neural Network and Machine Learning based Classifiers for Huntington Disease Prediction from Human DNA Sequence.
IEEE/ACM Trans Comput Biol Bioinform
November 2024
Article Synopsis
- Huntington Disease (HD) is a neurodegenerative disorder causing issues like psychiatric problems, movement disorders, and weight loss, which must be identified early in life.
- A Deep Learning-based system analyzes human DNA sequences to predict HD by employing a Deep Neural Network (DNN) and other classifiers to determine DNA impact from HD.
- The research utilizes Chaos Game Representation for numerical DNA conversion, extracting key features for classification, with findings indicating DNN, Neural Network, SVM, and Random Forest achieving 100% accuracy, while Classification Tree with Forward Pruning reached 87%.