Publications by authors named "Vishesh Jain"

Unlabelled: Anthropometry of the penis holds significant cultural and clinical importance, reflecting male genital development and aiding in the early identification of abnormalities.

Objectives: To develop an age-related penile length nomogram for Indian children, to define a range of normalcy, and to develop age-matched controls for penile length assessment in managing conditions like hypospadias.

Methods: This is a cross-sectional study (Design) initiated post-Institute Ethics Committee clearance (Ethics) based on 1276 volunteers (boys) aged 1-14 years (Participants) presenting to a pediatric surgery clinic (Setting) for conditions not affecting penile length.

View Article and Find Full Text PDF

Background: Intranodal hemangiomas are rare benign vascular tumors of the lymph nodes, often misdiagnosed as malignant lymphadenopathies due to their clinical and radiological features. This case report and systematic review aim to elucidate the epidemiology, clinical profile, and therapeutic interventions for intranodal hemangioma, enhancing diagnostic accuracy and management.

Methods: A systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

View Article and Find Full Text PDF

Background: A discrepancy between the true and measured value of stretched penile length (SPL) may be a result of errors that can either be systematic or random. Hence, it becomes important to focus on the quality of measurements to prevent any iatrogenic harm to the patients.

Objective: The objective of this study was to assess the magnitude of intra- and interobserver variations in the measurement of SPL with the SPLINT technique.

View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on the genetic underpinnings of congenital pouch colon (CPC), highlighting the lack of research in this area despite extensive clinical documentation.
  • A total of 20 cases of CPC and 52 controls were analyzed, revealing multiple genetic variants in 11 significant genes linked to critical functions like mucosal barrier integrity and colonic muscle development.
  • The results suggest that validating these findings with larger, diverse clinical samples and functional studies is essential to understand the genetic factors contributing to CPC better.
View Article and Find Full Text PDF

Background: The occupational hazards of glutaraldehyde are well known; the possibility of harm to the patients has been highlighted in the form of isolated reports only.

Objective: To synthesize evidence for contact mucosal injury or injury due to intraperitoneal instillation of glutaraldehyde following its use during laparoendoscopy.

Materials And Methods: The current review is Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) compliant.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to identify genetic markers associated with spina bifida in Indian patients by conducting whole-exome sequencing on three different cases.
  • The analysis revealed multiple pathogenic variants linked to spina bifida, including MTRR, CC2D2A, and ZIC2, while novel markers common to all patients were also identified.
  • Results indicate that the genetic landscape of spina bifida in Indians shows notable diversity compared to studies from other regions, contributing to a new catalog of variants relevant to the condition.
View Article and Find Full Text PDF

Background: Virtual reality (VR) refers to a computer-generated simulation or environment that can be experienced and interacted with by a person through special electronic equipment, such as a headset with a screen and motion-tracking sensors. VR has been used as a distraction technique to alleviate pain and discomfort during medical procedures or as an alternative to traditional pain medication. This article explores VR's effectiveness in reducing pain in pediatric patients undergoing painful clinical procedures.

View Article and Find Full Text PDF

Unlabelled: During face mask ventilation, invariably, some air enters the esophagus rather than the airways; this results in gastric insufflation while the esophagus is intact or loss of tidal volume in patients with a cervical esophagostomy (Cx-esophagostomy).

Objective: The objective of the study was to report the indigenous use of an electrocardiography (ECG) electrode in successfully occluding the Cx-esophagostomy to prevent inadvertent loss of tidal volume.

Materials And Methods: Twenty-nine observations were recorded on 27 patients (mean age: 10.

View Article and Find Full Text PDF

Introduction: Pelvi-Ureteric Junction Obstruction (PUJO) is a common cause of hydronephrosis (HDN) in children. While ultrasonography (USG) is useful for initial assessment and grading of hydronephrosis, it cannot differentiate obstructive from non-obstructive cases. Renal Dynamic Scintigraphy (RDS) confirms the diagnosis but involves ionizing radiation exposure.

View Article and Find Full Text PDF

Introduction: Children ≤5 years of age with Ewing's sarcoma (ES) possibly have a distinct disease biology, data on which are scarce. We evaluated clinical features, outcomes, and prognostic factors of ES among children with age ≤5 years.

Methods: Children with ES registered between 2003 and 2019 were included.

View Article and Find Full Text PDF

Objectives: To assess the clinico-pathological features, management and outcomes, amongst extracranial malignant germ cell tumors (MGCTs) in children treated primarily at a tertiary care center in a resource-challenged nation.

Methods: The prospectively maintained data for children below 14 y of age treated for extracranial MGCT from May 1994 to January 2023 was analyzed for patient characteristics, management, event-free survival (EFS) and overall survival (OS) and factors effecting survival. Events was defined as death, recurrence and progression.

View Article and Find Full Text PDF

Zinner syndrome, a rare congenital anomaly affecting males, is characterized by atresia of the ejaculatory duct, seminal vesicle cysts, and ipsilateral renal agenesis. This case report details a 2-year-old boy successfully treated with laparoscopic excision of a dilated vas deferens and seminal vesicle cyst. The rarity of Zinner syndrome in pediatric patients underscores the importance of understanding its diagnosis and minimally invasive surgical management.

View Article and Find Full Text PDF

Purpose: Wilms' tumor (WT) is a rare kidney cancer that primarily affects children. Exosomes are extracellular vesicles that cargo nucleic acids, proteins,etc. for cellular communication.

View Article and Find Full Text PDF

Stomal prolapse is one of the most common complications of enterostoma. Stoma if persistent and significant often requires revision of stoma. The techniques described often require laparotomy with resection or internal fixation of the bowel.

View Article and Find Full Text PDF

Introduction: A scientometric analysis was conducted to characterize the global research publications in extrahepatic portal venous obstruction (EHPVO), and state-of-the-art visualization graphics were generated to provide insight into specific bibliometric variables.

Materials And Methods: The Web of Science database was accessed for research productivity and bibliometric variables of countries, institutions, authors, journals, and content analysis of top-20 cited documents were performed. Collaborative networks and co-occurrence of keywords map were generated using VOSviewer software.

View Article and Find Full Text PDF

Aim: In addition to the well-known toxicities of treatment, survivors of pediatric solid tumors can also develop other health-related conditions. They may either be an indirect consequence of therapy or could be unrelated to their prior history of malignancy. We aim to evaluate the nontoxicity related health conditions in survivors of pediatric solid tumors.

View Article and Find Full Text PDF

Aims: The aim of this study was to compare the immediate and long-term outcomes after high spermatic vessel ligation (HSVL) and low spermatic vessel ligation (LSVL) in a high undescended testis (UDT) model in rats.

Materials And Methods: A prospective randomized controlled study was conducted on 24 male Wistar rats. The rats were randomly divided into three groups.

View Article and Find Full Text PDF

Introduction: Despite the advancements in technique and technology, urethrocutaneous fistula (UCF) formation continues to be the most common complication after hypospadias repair.

Objective: The objective of the current synthesis is to define the indications of PATIO technique for UCF repair.

Materials And Methods: The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

View Article and Find Full Text PDF

Nutritional status is an important aspect of childhood cancer, with a bearing on the disease and subsequent survivorship. We sought to evaluate the long-term anthropometric outcomes in a cohort of pediatric solid tumor survivors treated between 1994 and 2016. Anthropometry was noted at the time of presentation, after completion of therapy, and at the last follow-up.

View Article and Find Full Text PDF

Introduction: Surgical complication following esophageal atresia repair is one of the several factors known to influence the final outcomes. Early identification of such complications may help in timely institution of therapeutic measures and translate into improved prognosis.

Objective: The objective of this study was to evaluate the role of procalcitonin in early prediction of the adverse events after surgery in patients of esophageal atresia and the temporal relationship with clinical manifestations and other inflammatory biomarkers such as C-reactive protein (CRP).

View Article and Find Full Text PDF