Publications by authors named "Vishali Sharma"

Article Synopsis
  • The article reviews literature on managing symptomatic physiological hydronephrosis during pregnancy and compares various intervention methods.
  • An extensive search through databases like PubMed revealed that conservative treatments, such as regular pain relief, positioning, and antibiotics, are generally preferred and effective for most patients.
  • While conservative management is usually the first choice, more invasive procedures like ureteric stent insertion or nephrostomy are reserved for a small number of cases where symptoms persist despite conservative care.
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Ubiquitin proteasome system (UPS) and autophagy both pathways are involved in clearing the nonessential cellular components and also crosstalk during cellular response to normal and stress conditions. The F-box motif proteins constitute the SCF-E3 ligase complex of the UPS pathway in Saccharomyces cerevisiae and are involved in the substrate recruitment for ubiquitination. The ATG1 encoded Atg1p, a conserved serine-threonine kinase is crucial for the autophagy process.

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A rare metal-free nucleophilic nitrosoarene catalysis accompanied by highly hydrogen-bond-donor (HBD) solvent, 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP), organocatalytically converts arylmethyl halides to aromatic carbonyls. This protocol offers an effective means to access a diverse array of aromatic carbonyls with good chemoselectivity under mild reaction conditions. The activation of arylmethyl halides by HFIP to generate stable carbocation and autoxidation of in situ generated hydroxylamine to nitrosoarene in the presence of atmospheric O are the keys to success.

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