Publications by authors named "Vishal K Chavda"
Introduction: Neurosurgery is evolving with new techniques and technologies, relies heavily on high-quality education and training. Social networks like Twitter, Facebook, Instagram and LinkedIn have become integral to this training. These platforms enable sharing of surgical experiences, fostering global knowledge-sharing and collaboration among neurosurgeons.
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- The study investigates the link between D-dimer levels and stroke in cancer patients, highlighting that higher D-dimer levels may indicate the presence of cancer in stroke patients.
- A systematic review and meta-analysis were conducted, examining 495 articles, ultimately including six high-quality studies with 2,651 ischemic stroke patients (13.97% with cancer).
- Results show that stroke patients with active cancer had significantly higher D-dimer levels compared to those without cancer, suggesting D-dimer could be a useful biomarker for predicting cancer in stroke cases.
Background: Vascular injuries occur in approximately 25% of all penetrating neck traumas, with carotid artery injuries being particularly lethal. Penetrating neck injuries are potentially fatal. Vascular injuries occur in approximately 25% of cases, which can lead to the formation of arteriovenous fistulas.
View Article and Find Full Text PDFChanges in protein structure and function, alteration in protein-protein interaction, and significant difference in protein concentration inside the body could play an important role in indicating the pathological evidence of abnormalities before the development of clinical symptoms and act as a critical detection and diagnostic tool commonly known as biomarkers. Biomarkers play important roles in the diagnosis of various chronic diseases, including cancer. Neurodegenerative disorders, including Parkinson's, Alzheimer's, Huntington's, prion, and multiple sclerosis, are well characterized by neuronal deterioration, resulting in precise modifications of neuronal proteins.
View Article and Find Full Text PDFBackground: Numerous studies suggest that non-steroidal anti-inflammatory drugs reduce cancer cell proliferation, progression, angiogenesis, apoptosis, and invasiveness.
Objective: The current study focuses on the evaluation of novel mefenamic acid derivatives for the treatment of hepatocellular carcinoma.
Methods: Derivatives were subjected to molecular modeling for prediction of pharmacological activity using software, followed by synthesis and in vitro assay.