Publications by authors named "Viroje Chongkolwatana"
Background: Chikungunya (CHIKV), dengue (DENV), and Zika (ZIKV) viruses are of concern due to the potential of transfusion transmission in blood, especially in regions such as Southeast Asia where the viruses are endemic. The recent availability of nucleic acid testing (NAT) to screen blood donations on an automated platform provides the opportunity to detect potentially infectious units in asymptomatic donors.
Study Design And Methods: Three thousand blood donations from Vietnam and 6000 from Thailand were screened with a real-time polymerase chain reaction (PCR) test (cobas CHIKV/DENV, Roche Diagnostics, Indianapolis, IN) and equal numbers on cobas Zika (Roche Diagnostics).
Article Synopsis
- * Scientists think that using freeze-dried platelets (something usually thrown away) could help speed up the healing process, so they made a special gel from it called IF-PG.
- * In tests with rats, IF-PG helped wounds heal faster and more effectively compared to a common antibiotic gel, but more research is needed to fully understand its benefits.
Background: There has been an increased interest in platelet-derived microparticles (PMPs) in transfusion medicine. Little is known about PMP status during the preparation of platelet concentrates for transfusion.
Aim: The aim of this study is to compare the PMP levels in platelet components prepared using the buffy coat (BC), platelet-rich plasma platelet concentrate (PRP-PC), and apheresis (AP) processes.
Background: The problem of red blood cell (RBC) shortage occurs because of the expanding demand for blood utilization and the dfficulties in donor recruitment and retention. Resources can be maximized by using current technology to collect two units of RBC from the same donor during a single collection session.
Objective: To evaluate the performance, collection efficiency (CE), production cost, and donor satisfactions of two commercially available blood cell separators (BCS) for double dose red cell (DDRC) collection.
Background: Killer cell immunoglobulin-like receptors (KIRs) are members of a group of regulatory molecules found on the natural killer (NK) cells that regulate NK cells function by interacting with the human leukocyte antigen (HLA) class I molecules or ligands. The effects of KIR genes on the outcome of hematopoietic stem cell transplantation (HSCT) are still controversial.
Objective: To investigate the distribution of KIR genes in HLA-identical sibling and the effect of KIR genes on the outcome of HSCT.
Background: An evaluation by the National Blood Center, the Thai Red Cross Society, of two commercial multiplex nucleic acid tests (NATs; the Chiron PROCLEIX ULTRIO test and the Roche Cobas TaqScreen MPX test) for screening Thai blood donors for hepatitis B virus (HBV), hepatitis C virus, and human immunodeficiency virus Type 1 identified 175 HBV NAT-reactive/hepatitis B surface antigen (HBsAg)-negative donors. The classification of the HBV infection of these donors was confirmed by follow-up testing.
Study Design And Methods: Index samples were tested for HBV serologic markers and HBV viral loads were determined.
Purpose: To compare the survival of human fibroblasts in freeze-dried irradiated platelets, fresh concentrated platelets, or foetal bovine serum.
Methods: 3, 10, 30, and 100 micrograms protein/ml of freeze-dried irradiated platelets or fresh concentrated platelets, or 5%, 15%, and 50% of foetal bovine serum were each added to the culture medium with human fibroblasts. Controls had no growth factors or serum added.
One-year experience of nucleic acid technology testing for human immunodeficiency virus Type 1, hepatitis C virus, and hepatitis B virus in Thai blood donations.
Transfusion
June 2009
Background: Blood donations collected at the National Blood Center, the Thai Red Cross Society, Bangkok, in 2007 were tested by nucleic acid amplification technology (NAT) using the Chiron TIGRIS/Procleix Ultrio test and the Roche cobas s 201/cobas TaqScreen multiplex (MPX) test.
Study Design And Methods: The sensitivity, specificity, and robustness were determined by testing 486,676 seronegative blood donations. Samples from each day of collection were divided into two sets; the odd-numbered samples were tested individually on the TIGRIS and the even-numbered samples were tested in pools of 6 on the cobas s 201.