Publications by authors named "Viridiana Morales-Sanchez"

Article Synopsis
  • The study focused on the ethyl acetate extract from endophytic fungus SPH2, isolated from an endemic plant, assessing its biocontrol properties against various plant pathogens, pests, and ticks.
  • SPH2 extracts displayed strong fungicidal and ixodicidal abilities at different fermentation times, with compound Mellein showing significant effects against ticks and fungi.
  • The findings indicate that SPH2 could be a valuable resource for developing ixodicidal products, particularly rich in Mellein, while confirming that the harmful mycotoxin ochratoxin A was not present in the fermentation conditions used.
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Since 1980, many species and different strains from endophytic genera of Phomopsis, Fusarium, Pestaliopsis and Aspergillus have been studied because of their ability to produce medicinal compounds found in their host plants. Some of these medicinal agents such as Taxol, Brefeldine A, Camptothecin and Podophyllotoxin are being produced in large-scale after an optimization process. However, the potential of fungal endophytes to produce host-like medicinal compounds remains largely unexplored.

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Ethnopharmacological Relevance: Cyrtopodium macrobulbon ("cañaveral") has been long used in Mexican traditional medicine for the treatment of painful urinary ailments ("mal de orin") in men. This study was conducted (i) to establish the potential acute toxicity and the antinociceptive activity of some preparations of Cyrtopodium macrobulbon, in order to demonstrate its preclinical efficacy for treating symptoms of "mal de orin"; and (ii) to determine the chemical composition and quality control parameters of this medicinal orchid.

Materials And Methods: The antinociceptive effect was assessed using the acetic acid-induced writhing and the hot-plate tests.

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