Publications by authors named "Virginie Nguyen-Khac"

Article Synopsis
  • Children with X Linked Hypophosphatemia (XLH) experience significant bone issues and may also have distinct muscle characteristics compared to typically developed (TD) children.
  • A study used MRI to analyze muscle morphology in 11 XLH patients and 15 TD children, hypothesizing that XLH would show noticeable differences that could contribute to their limping.
  • Results indicated that most muscle lengths and volumes in XLH patients were smaller than in TD children, with the exception of the medius/minimus gluteus muscles, suggesting a varied muscle structure associated with the condition.
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Background: X-linked hypophosphataemia causes bone deformities and gait abnormalities that tend to worsen with age in the absence of appropriate treatment. However, doctors do not currently use quantitative tools to characterize these symptoms and their possible interactions.

Methods: Radiographs and 3D gait data from 43 non-surgical growing children with X-linked hypophosphataemia were acquired prospectively.

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Context: Children with X-linked hypophosphatemic (XLH) rickets have muscle weakness that severely impairs their function. Intermuscular and intramuscular adipose tissue (IMAT and intraMAT, respectively) may contribute to this muscle weakness.

Objective: This work aimed to compare IMAT and intraMAT in XLH children vs typically developing (TD) children.

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Introduction: The aim of the present study was to define indications for talectomy in congenital paralytic, dystrophic or idiopathic, inveterate or recurrent, clubfoot.

Hypothesis: Talectomy is a valid option for paralytic, dystrophic or idiopathic, inveterate or recurrent, clubfoot.

Patients And Methods: A single-center retrospective series comprised 52 clubfeet in 31 patients.

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Introduction: Percutaneous Achilles tenotomy (PAT) was recently added to functional treatment of congenital talipes equinovarus (aka clubfoot). The aim of this study was to determine the relevance of a carefully chosen radiological criterion for the PAT indication and to evaluate its results.

Hypothesis: When the tibiocalcaneal angle (aTiCa) is larger than 75° at 4 months, doing PAT will improve the results of the functional method in the medium term and will reduce the surgery rate.

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