Publications by authors named "Virginia Watkins"

Objective: Physical activity in pregnancy decreases the risk of adverse maternal and neonatal outcomes. This study evaluates the association between first trimester physical activity, assessed by Kaiser Physical Activity Survey (KPAS) scores, and adverse perinatal outcomes.

Study Design: This is a secondary analysis of a prospective cohort study in which patients were administered the KPAS in each trimester.

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Article Synopsis
  • The study investigates pregnancy and delivery outcomes for women with hereditary hemorrhagic telangiectasia (HHT), focusing on severe maternal morbidity (SMM) and other related complications.
  • A significant rise in HHT diagnoses during pregnancy was observed from 2010 to 2021, with women diagnosed showing higher rates of complications compared to those without HHT.
  • Key findings include increased risks for SMM, preterm birth, cesarean delivery, respiratory bleeding, and cerebrovascular complications in pregnant women with HHT.
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Objective: To systematically review and meta-analyze alloimmunization among recipients of red blood cells (RBCs) matched for ABO blood type and Rhesus D (ABO+D) antigen compared with those also matched for c, E, and Kell (cEK).

Data Sources: Four online databases (Medline, Scopus, EMBASE, ClinicalTrials.gov ) were searched from March 28, 2023, to April 1, 2024.

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Importance: Although the risk of parvovirus B19 infection during pregnancy and subsequent risk of adverse fetal outcome are low, understanding management practices is essential for proper treatment of fetuses with nonimmune hydrops fetalis. In addition, continued investigation into delivery management, breastfeeding recommendations, and congenital abnormalities associated with pregnancies complicated by parvovirus B19 infection is needed.

Objective: This review describes the risks associated with parvovirus B19 infection during pregnancy and the management strategies for fetuses with vertically transmitted infections.

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Article Synopsis
  • The study investigates the combined effects of Hepatitis C virus (HCV) and intrahepatic cholestasis of pregnancy (ICP) on pregnancy outcomes, finding that both conditions independently increase the risk of severe maternal morbidity.
  • Using data from over 10 million deliveries, researchers categorized patients based on their HCV and ICP status to evaluate their maternal and obstetric outcomes.
  • Results showed that having both Hepatitis C and ICP significantly raises the odds of severe maternal complications compared to having neither condition.
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Background: Intrahepatic cholestasis of pregnancy is associated with a 4- to 10-fold increase in the risk of stillbirth in the absence of intervention, leading to recommendations for antenatal assessment, ursodiol use, and often preterm or early term delivery.

Objective: This study aimed to determine whether current management strategies for intrahepatic cholestasis of pregnancy mitigate the elevated risk of stillbirth at a population level.

Study Design: This was a retrospective cohort study using the 2015-2020 National Readmissions Database, an administrative database developed by the United States Agency for Healthcare Research and Quality.

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Background: Anemia is a commonly diagnosed comorbidity in pregnancy that is associated with increased risk of maternal and neonatal complications. Recent data demonstrate that maternal anemia is associated with higher umbilical artery and umbilical vein O content at the time of delivery.

Objective: This study aimed to examine the relationship between maternal anemia and electronic fetal monitoring patterns associated with fetal hypoxia.

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Background: Physical activity in pregnancy is associated with decreased risks of adverse pregnancy outcomes such as gestational diabetes and preeclampsia. However, the relationship between the amount and type of physical activity during pregnancy and subsequent labor outcomes remains unclear.

Objective: This study aimed to test the hypothesis that higher levels of physical activity across different lifestyle domains in pregnancy are associated with a shorter duration of labor.

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Background: Anemia is one of the most commonly diagnosed comorbidities in pregnancy and is known to increase the risk of obstetrical complications. However, little is known about the effect of anemia on placental oxygen transfer and fetal oxygenation.

Objective: This study examined the relationship between maternal anemia and fetal oxygenation status at delivery as measured by umbilical cord partial pressure of oxygen.

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Background: Maternal oxygen (O) administration is a commonly performed intrauterine resuscitation technique though to improve fetal oxygenation. However, hyperoxygenation is known to be harmful in both neonates and adults. Currently, there are no formal recommendations on whether a certain dose or duration of O may be most helpful in improving umbilical cord gases or neonatal outcomes.

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