Publications by authors named "Virginia Matallana Royo"

Article Synopsis
  • * Out of 87 patients, a significant majority transitioned to clinical remission and biologic remission after intensification, with no serious adverse events reported during the follow-up period.
  • * No differences in overall drug costs were observed with the new ADA 80 mg eow regimen compared to the standard treatment intensification.
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Introduction: Faecal microbiota transplantation (FMT) is a treatment supported by wide scientific evidence and proved to be very effective in the management of Clostridioides difficile infection (CDI). The objective of this study is to analyze its effectiveness and safety in a real clinical practice setting.

Methods: Retrospective, single-center and descriptive observational study in which all FMT performed between May 2016 and December 2020 were included.

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 Diagnosis and monitoring of ulcerative colitis (UC) includes conventional colonoscopy. This procedure is invasive and does not exclude small-bowel Crohn's disease (CD). Current therapeutic goals include mucosal healing which may lead to an increased number of endoscopic procedures in many patients.

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Background: Thiopurines are classically used in Crohn's disease (CD). Treatment fails in a proportion of patients either due to adverse events (AE) or lack of efficacy. Increasing use of anti-TNFα biologic drugs may have had impact on thiopurines usage.

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Introduction: The possibility of developing idiopathic portal hypertension has been described with thiopurine treatment despite compromises the prognosis of these patients, the fact its true prevalence is unknown.

Material And Methods: A cross-sectional study was conducted in a cohort of inflammatory bowel disease (IBD) patients followed at our unit, to determine the prevalence of diagnosis of idiopathic portal hypertension (IPH) and its relationship with thiopurine treatment.

Results: At the time of the analysis, 927/1,419 patients were under treatment with thiopurine drugs (65%).

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