Surgical Reconstruction of Ocular Surface Tumors Using Fibrin Sealant Tissue Adhesive.

Purpose: To evaluate the surgical outcomes of ocular surface reconstruction in corneal-conjunctival tumors using fibrin tissue adhesive.

Methods: A prospective noncomparative study was performed between May 2013 and February 2015. Patients were submitted to routine surgical procedure for corneal-conjunctival tumor excision followed by amniotic membrane graft transplantation using fibrin tissue adhesive (Evicel®, Omrix Biopharmaceuticals Ltd.

Risk Factors Associated With the Ophthalmoscopic Findings Identified in Infants With Presumed Zika Virus Congenital Infection.

Importance: The Zika virus (ZIKV) might cause microcephaly and ophthalmoscopic findings in infants of mothers infected during pregnancy.

Objective: To assess and identify possible risk factors for ophthalmoscopic findings in infants born with microcephaly and a presumed clinical diagnosis of ZIKV intrauterine infection.

Design, Setting, And Participants: We conducted a cross-sectional study at the Altino Ventura Foundation in Recife, Brazil, that included 40 infants with microcephaly born in Pernambuco state, Brazil, between May and December 2015.

Macular hole: 10 and 20-MHz ultrasound and spectral-domain optical coherence tomography.

Purpose: Optical coherence tomography (OCT) is valuable for macula evaluation. However, as this technique relies on light energy it cannot be performed in the presence of opaque media. In such cases, the ultrasound (US) may predict some macular features.

Optical coherence tomography enhanced depth imaging of choroidal tumors.

Purpose: To describe the spectral-domain optical coherence tomography (SD-OCT) features of choroidal tumors imaged using enhanced depth imaging (EDI) technique.

Design: Prospective observational case series.

Methods: One tumor each from 23 eyes of 23 patients was included.

A new device for ocular globe enucleation.

It is important to perfect the enucleation technique, especially in cases of intraocular malignancy, to obtain an adequate amount of tissue for histologic analysis and to cause a minimum amount of trauma to the remaining orbital structures. This study describes the use of a new device for ocular globe enucleation. The new instrument has been employed in 16 consecutive enucleation procedures with no complications.

[Histopathologic findings in retinoblastoma].

Objective: To study histopathological findings of enucleated eyes with retinoblastoma.

Methods: Twenty-eight cases of retinoblastoma treated by enucleation at the Federal University of São Paulo from December 2000 to October 2002 were histopathologically reviewed. Clinical data included age, gender, race, unilateral or bilateral involvement and previous treatment.

Relationship between histopathological features of chemotherapy treated retinoblastoma and P-glycoprotein expression.

Background: P-glycoprotein (P-gp) has been identified as a possible mediator of chemoresistance in retinoblastoma. The aim of this study was to determine the expression of P-gp in retinoblastoma treated with chemotherapy prior to enucleation.

Methods: Seventeen enucleated specimens of retinoblastoma from 16 patients were studied.

Ultrasound biomicroscopy features of iris and ciliary body melanomas before and after brachytherapy.

Background And Objective: To determine ultrasound biomicroscopy (UBM) features of iris and ciliary body melanomas before and after brachytherapy.

Patients And Methods: Four uveal anterior melanoma cases undergoing brachytherapy were retrospectively studied. All cases were examined by UBM prior to treatment and repeatedly after treatment.