An Overview of Monoclonal Antibodies.

Objective: To provide a brief overview of the development of monoclonal antibodies in immunotherapy, including a review of the mechanism of action and types, and indications for use.

Data Source: Peer-reviewed journal articles, book chapters, internet.

Conclusion: Monoclonal antibodies offer alternative treatment to cancer patients who have failed or progressed on standard chemotherapy.

Cancer Immunotherapy: An Evidence-Based Overview and Implications for Practice.

Background: Significant research progress has been made in immunotherapies since the mid-1990s, and this rapid evolution necessitates evidence-based education on immunotherapies, their pathophysiology, and their toxicities to provide safe, effective care.
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Objectives: The aim of this article is to provide an evidence-based overview, with implications for practice, of checkpoint inhibitors, monoclonal antibodies, oncolytic viral therapies, and chimeric antigen receptor T-cell therapies.