Agricultural Soil as a Reservoir of with Potential Risk to Public Health.

is an opportunistic pathogen with a high capacity to adapt to different factors. The aim of this study is to analyze the pathogenicity in strains and their resistance to heavy metals and antibiotics, in agricultural soil of the state of Tamaulipas, Mexico. Susceptibility to 16 antibiotics was tested using the Kirby-Bauer method (CLSI).

The Global Rise of ESBL-Producing in the Livestock Sector: A Five-Year Overview.

β-lactam antibiotics are a key element in the treatment of bacterial infections. However, the excessive use of these antibiotics has contributed to the emergence of β-lactam-resistant enterobacteria, including . One of the main challenges facing the public health sector is antibacterial resistance (ABR), mainly due to limited options in its pharmacological treatment.

Antibiotic resistant Escherichia coli strains in healthy pets from Tamaulipas, Mexico.

Antibiotic resistance constitutes a significant public health challenge, with diverse reservoirs of resistant bacteria playing pivotal roles in their dissemination. Among these reservoirs, pets are carrying antibiotic-resistant strains. The objective of this study was to assess the resistance profiles of Escherichia coli, and the prevalence of extended-spectrum β-lactamase (ESBL) producing E.

Prevalence and Antimicrobial Resistance of in Different Raw Food from Reynosa, Tamaulipas, Mexico.

() is an opportunistic foodborne pathogen that causes listeriosis in humans and animals, reaching up to 30% case mortality. There are only a few reports in Mexico about the strains found in various foods. The aim of this study was to determine the prevalence of , serogroups, virulence genes, and antimicrobial resistance in different foods from Reynosa, Tamaulipas, Mexico.

Ligand- and Structure-Based Virtual Screening Identifies New Inhibitors of the Interaction of the SARS-CoV-2 Spike Protein with the ACE2 Host Receptor.

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a fast-spreading viral pathogen and poses a serious threat to human health. New SARS-CoV-2 variants have been arising worldwide; therefore, is necessary to explore more therapeutic options. The interaction of the viral spike (S) protein with the angiotensin-converting enzyme 2 (ACE2) host receptor is an attractive drug target to prevent the infection via the inhibition of virus cell entry.

and Biological Activity of Two Aryloxy-naphthoquinones in Mice Infected with Strains.

Background: Chagas disease, a condition caused by Trypanosoma cruzi, is an endemic disease in Latin American countries that affects approximately eight million people worldwide. It is a continuing public health problem. As nifurtimox and benznidazole are the two pharmacological treatments currently used to treat it, the present research proposes new therapeutic alternatives.

Antimicrobial resistance, virulence genes, and ESBL (Extended Spectrum Beta-Lactamase) production analysis in E. coli strains from the Rio Grande/Rio Bravo River in Tamaulipas, Mexico.

The Rio Grande/Rio Bravo River is used as a major water supply for diverse recreational, household, and industrial activities in Northeast Tamaulipas, Mexico, and South Texas. In this study, we sampled surface water from 38 sites along Rio Grande/Rio Bravo River (Díaz Ordaz, Reynosa and Matamoros). We isolated 105 E.

Extended-Spectrum β-Lactamase-Producing Isolated from Food-Producing Animals in Tamaulipas, Mexico.

Extended-spectrum β-lactamase (ESBL)-producing has become an important global problem for the public health sector. This study aims to investigate the antimicrobial resistance profile among living food-producing animals in Tamaulipas, Mexico. A total of 200 fecal samples were collected from bovines, pigs, chickens and sheep.

Molecular and Antimicrobial Susceptibility Characterization of Isolates from Bovine Slaughterhouse Process.

Antimicrobials are routinely used in human and veterinary medicine. With repeated exposure, antimicrobials promote antibiotic resistance, which poses a threat to public health. In this study, we aimed to determine the susceptibility patterns, virulence factors, and phylogroups of isolates during the killing process in a bovine slaughterhouse.

Evaluation of Retail Meat as a Source of ESBL in Tamaulipas, Mexico.

In recent decades, the appearance of a group of strains resistant to most β-lactam antibiotics, called extended-spectrum β-lactamases (ESBLs), has greatly impacted the public health sector. The present work aimed to identify the prevalence of ESBL-producing strains in retail meat from northeast Tamaulipas. A total of 228 meat samples were obtained from 76 different stores.

Characterization of triatomine bloodmeal sources using direct Sanger sequencing and amplicon deep sequencing methods.

Knowledge of host associations of blood-feeding vectors may afford insights into managing disease systems and protecting public health. However, the ability of methods to distinguish bloodmeal sources varies widely. We used two methods-Sanger sequencing and amplicon deep sequencing-to target a 228 bp region of the vertebrate Cytochrome b gene and determine hosts fed upon by triatomines (n = 115) collected primarily in Texas, USA.

spp. from Plant Growth-Promoting Bacteria to Their Use in Bioremediation.

Xenobiotic contamination, a worldwide environmental concern, poses risks for humans, animals, microbe health, and agriculture. Hydrocarbons and heavy metals top the list of toxins that represent a risk to nature. This review deals with the study of sp.

Draft Genome Sequence of a Uropathogenic Escherichia coli Sequence Type 44 Strain Carrying Multiple Antimicrobial Resistance Genes.

Escherichia coli is a reservoir of antimicrobial resistance genes (ARGs). Here, we report the draft genome sequence of an E. coli strain (31HGR-CBG) that was isolated from a urine sample in Tamaulipas, Mexico.

RDMycobacterium tuberculosis strains associated with isoniazid resistance in Northern Mexico.

Background: It has been established that the genomic background of Mycobacterium tuberculosis may influence disease progression, in particular for the Beijing family and the Latin American and Mediterranean (LAM)/RD strains. The purpose of this study was to evaluate the prevalence of the LAM/RD genotype in cases of tuberculosis from Mexico and their drug susceptibility profile.

Methods: Two hundred eighteen M.

Advances in Control Strategies against . A Review.

The strategies for controlling the insect pest have been developing over the past four decades; however, the insecticide resistance and the remarkable adaptability of this insect have hindered its success. This review first analyzes the different chemical compounds currently available and the most promising options to control . Then, we analyze the metabolites obtained from plant extracts with antifeedant, repellent, insecticide, or ovicide effects that could be environmentally friendly options for developing botanical insecticides.

Identification and Characterization of the CRISPR/Cas System in Strains From Diverse Sources.

The CRISPR-Cas [clustered regularly interspaced short palindromic repeats and the CRISPR-associated genes (Cas)] system provides defense mechanisms in bacteria and archaea vs. mobile genetic elements (MGEs), such as plasmids and bacteriophages, which can either be harmful or add sequences that can provide virulence or antibiotic resistance. is a Gram-positive bacterium that could be the etiological agent of important soft tissue infections that can lead to bacteremia and sepsis.

Virtual Screening of FDA-Approved Drugs against Triose Phosphate Isomerase from and Identifies Inhibitors of Their Trophozoite Growth Phase.

Infectious diseases caused by intestinal protozoan, such as () and () are a worldwide public health issue. They affect more than 70 million people every year. They colonize intestines causing primarily diarrhea; nevertheless, these infections can lead to more serious complications.

Multidrug Resistance of Strains Isolated From Bovine Feces and Carcasses in Northeast Mexico.

In this work, the antimicrobial resistance profile of strains ( = 248) isolated from bovine feces and carcass samples from Tamaulipas, Mexico, was evaluated. Susceptibility to 12 antibiotics conventionally used in human and veterinary treatments was determined according to Clinical and Laboratory Standards Institute guidelines. Genes encoding resistance to tetracycline ( and ), streptomycin (A), aminoglycoside (A), and β-lactamase ( and ) were investigated by PCR.

Antimicrobial susceptibility pattern of species isolated from Mexico.

Background: species are multi-resistant bacteria with ability to cause opportunistic infections.

Objective: We isolated 45 species from soil, sewage and the clinic with the aim of investigating their susceptibility to commonly used antimicrobial agents.

Methodology: The identities of isolates were confirmed with 16S rRNA gene sequence and MALDI-TOF analysis.

RDMycobacterium tuberculosis strains associated with isoniazid resistance in Northern Mexico.

Background: It has been established that the genomic background of Mycobacterium tuberculosis may influence disease progression, in particular for the Beijing family and the Latin American and Mediterranean (LAM)/RD strains. The purpose of this study was to evaluate the prevalence of the LAM/RD genotype in cases of tuberculosis from Mexico and their drug susceptibility profile.

Methods: Two hundred eighteen M.

In Silico Analysis of FDA Drugs as P2X4 Modulators for the Treatment of Alcohol Use Disorder.

Recent studies have shown the potential application of ivermectins in the treatment of alcohol use disorder (AUD). Ivermectin is a positive allosteric modulator (PAM) of P2X4R and this molecule exerts its action in the transmembrane region (known as the TM region) of trimeric channel structure (the pocket formed by Asp331, Met336, Trp46, Trp50, and Tyr42). The aim of this study is to identify FDA drugs with potential PAM properties, by exploring the P2X4Rs from four organisms (Danio rerio, Mus musculus, Rattus norvegicus, and Homo sapiens).