Publications by authors named "Viren R Amin"
Article Synopsis
- Isovaleric acidemia (IVA) is a metabolic disorder caused by a deficiency of isovaleryl-CoA dehydrogenase, leading to serious gastrointestinal and neurological symptoms that can result in long-term disability or death if not detected early.
- In a study involving 13 Mexican patients, common symptoms included vomiting, lethargy, and seizures, with mean levels of isovalerylcarnitine significantly above normal in symptomatic patients and newborns.
- The research revealed a complex genetic background with 14 variants in the IVD gene, showing a long diagnostic delay; thus, raising physician awareness and incorporating newborn screening with molecular analysis is crucial for effective management and early detection of this treatable condition.
During early lactation, many dairy cows develop fatty liver, which is associated with decreased health and reproductive performance. Currently, fatty liver can be detected reliably only by using liver biopsy followed by chemical or histological analysis, which is not practical in most on-farm situations. We tested whether digital analyses of hepatic ultrasonograms can be used to detect non-invasively fatty liver and estimate liver triacylglycerol content.
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