Publications by authors named "Viren Lad"
Article Synopsis
- Sphingolipids play important roles in skin health, and a high-fat, high-cholesterol diet negatively impacts skin and hair by altering levels of specific lipids, particularly ceramides and glucosylceramide.
- Chronic consumption of this diet leads to increased levels of lactosylceramide and inflammation, which results in skin issues like discoloration and hair loss in a mouse model of atherosclerosis.
- Targeting glycosphingolipid synthesis using a specific inhibitor can reverse these adverse effects, highlighting a potential therapeutic strategy for skin and hair-related conditions in humans.
