Publications by authors named "Viraj R Muthye"
Myxozoans are a monophyletic taxon of approximately 2,400 described species of parasites from the phylum Cnidaria. The recent focus on their negative impacts on fisheries, on their evolution from free-living ancestors, and on their emergence into new fish host populations has stressed the critical need for genomic resources for this parasitic group. Here, we describe the genome assembly and annotation of Myxobolus rasmusseni, an emerging parasite of fathead minnows in Alberta, Canada.
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- Pathogens use sophisticated strategies like molecular mimicry to manipulate host signaling pathways.
- In this study, researchers developed a bioinformatics pipeline to identify molecular mimicry between human proteins and those of 32 pathogenic species, finding that fungi and protozoans had more mimicry candidates than bacteria.
- The analysis uncovered 1,878 mimicked regions in 1,439 human proteins, highlighting their potential role in biological processes, particularly in extracellular matrix organization, while noting that immune-related proteins were less frequently targeted.
- This research enhances our understanding of host-pathogen interactions and could aid in developing new therapeutic strategies.