Publications by authors named "Viraj J Parikh"

Article Synopsis
  • Intraperitoneal drains are used after pancreatic surgery to reduce complications, especially in patients at risk for postoperative pancreatic fistulas (CR-POPF).
  • A study analyzed data from over 4,000 cases to see whether using multiple drains is better than a single drain for reducing complications.
  • Results showed that using one or two drains both help mitigate complications, but using no drains significantly increases the risk of problems and mortality, regardless of the patient's risk level.
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Background: The MC3R haplotype C17A + G241A, which encodes a partially inactivated receptor, has high prevalence in individuals of predominately African ancestry. In pediatric cohorts, homozygosity for this common variant has been associated with obesity, reduced lean mass, and greater fasting insulin. However, metabolic and body composition measures have not been well studied in adults with this haplotype.

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Aims: Epigenetic regulators, including microRNAs (miRNAs), are implicated in type 2 diabetes, but evidence linking circulating miRNAs in pregnancy and risk of gestational diabetes (GDM) is sparse. Potential modifiers, including pre-pregnancy overweight/obesity and offspring sex, are unexamined. We hypothesized that circulating levels of early-mid-pregnancy (range 7-23weeks of gestation) candidate miRNAs are related to subsequent development of GDM.

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