Nosocomial outbreak caused by disinfectant-resistant in an adult intensive care unit, Hungary, February to March 2022.

In 2022, an outbreak with severe bloodstream infections caused by occurred in an adult intensive care unit (ICU) in Hungary. Eight cases, five of whom died, were detected. Initial control measures could not stop the outbreak.

Genomic Epidemiology of C2/H30Rx and C1-M27 Subclades of ST131 Isolates from Clinical Blood Samples in Hungary.

Extended-spectrum β-lactamase-producing ST131 has become widespread worldwide. This study aims to characterize the virulome, resistome, and population structure of ST131 isolates from clinical blood samples in Hungary. A total of 30 C2/H30Rx and 33 C1-M27 ST131 isolates were selected for Illumina MiSeq sequencing and 30 isolates for MinION sequencing, followed by hybrid de novo assembly.

Groundwater, soil and compost, as possible sources of virulent and antibiotic-resistant Pseudomonas aeruginosa.

is a major public health concern all around the world. In the frame of this work, a set of diverse environmental isolates with various antibiotic resistance profiles were examined in a virulence model. Motility, serotypes, virulence factors and biofilm-forming ability were also examined.

Characterization of Clinical Vancomycin-Resistant Enterococcus faecium Isolated in Eastern Hungary.

Objectives: The aim of our study was to characterize and elicit the genetic relatedness of emerging vancomycin-resistant enterococci (VRE) isolated between 2012 and 2015 at a teaching hospital in Debrecen, Hungary.

Results: Altogether 43 nonduplicate vancomycin-resistant Enterococcus faecium (VREfm) clinical isolates were obtained. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry was used for species identification.

Dissemination of VanA-Type Enterococcus faecium Isolates in Hungary.

Although vanA carrying Enterococcus faecium human clinical isolates have been rarely found in Hungary before 2012, they have been detected in continuously increasing numbers since then. To identify factors associated with their dissemination, we investigated the clonal relatedness and plasmids of 30 vanA carrying E. faecium isolates originating from different Hungarian healthcare institutions from 2012 to 2014.