The Impact of Surfactant Structures and High-Speed Mixing Dynamics in Achieving Nano-Sized Emulsions with Simple High-Speed Homogenization.

Purpose: This study investigates the impact of various mixing parameters and surfactant combinations on the physical characteristics of nanoemulsions produced using high-speed homogenization. Nanoemulsions are explored for their capacity to enhance transdermal drug delivery in pharmaceutical and cosmetic contexts.

Methods: Employing a standard high-speed homogenizer typical in the cosmetic industry, we tested different combinations of Polysorbate (Tween®) and Sorbitan ester (Span®) surfactants under single and intermittent process configurations.

Thermoregulatory effects of guava leaf extract-menthol toner application for post-exercise use.

Context: L. (Myrtaceae) leaf contains a wide variety of bioactive compounds that contribute valuable effects on human well-being.

Objective: This study investigates the influence of guava leaf extract-menthol toner on thermoregulation, including perspiration, skin temperature, and recovery heart rate.

Antioxidant, anti-collagenase and anti-elastase activities of Phyllanthus emblica, Manilkara zapota and silymarin: an in vitro comparative study for anti-aging applications.

Context Phyllanthus emblica L. (Euphorbiaceae) (amla), Manilkara zapota L.P.

Formulation of microemulsion systems for dermal delivery of silymarin.

Silymarin is a standardized extract from Silybum marianum seeds, known for its many skin benefits such as antioxidant, anti-inflammatory, and immunomodulatory properties. In this study, the potential of several microemulsion formulations for dermal delivery of silymarin was evaluated. The pseudo-ternary phase diagrams were constructed for the various microemulsion formulations which were prepared using glyceryl monooleate, oleic acid, ethyl oleate, or isopropyl myristate as the oily phase; a mixture of Tween 20®, Labrasol®, or Span 20® with HCO-40® (1:1 ratio) as surfactants; and Transcutol® as a cosurfactant.