Publications by authors named "Violetta Lozovyy"
In massive pulmonary embolism (PE), anticoagulation and thrombolytics may increase the risk of retroperitoneal bleeding following vascular cannulation for extracorporeal hemodynamic support resulting in abdominal compartment syndrome (ACS). A 27-year-old women at 33 weeks of gestation presented with acute chest pain and shortness of breath. Massive PE was diagnosed.
View Article and Find Full Text PDFPro-pregnancy hormone progesterone (P4) helps to maintain a quiescent status of uterine tissues during gestation. However, P4's functional role in maintaining fetal membrane (amniochorion) integrity remains unclear. P4 functions through its membrane receptors (progesterone receptor membrane components (PGRMCs)) as fetal membrane cells lack nuclear receptors.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to analyze how taking medications during early pregnancy affects the fetal fraction (FF) levels in women undergoing cell-free DNA (cfDNA) testing, comparing those on medications to those not on any medications.
- - Results showed that women taking two or more medications had significantly lower FF levels compared to those not taking medications, with obesity also negatively impacting FF levels.
- - Specifically, metformin was linked to a 1.8% reduction in mean FF, suggesting that both medication use and maternal obesity should be factored into discussions about cfDNA testing outcomes and their limitations.